Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5322183 | 0.90 | DRD2 (0.49) | DRD2ADRA1ACHRM2CCR5AKR1C3 | |
| SCHEMBL5324921 | 0.84 | ALDH1A1 (0.41) | DRD2ADRA1ACHRM2CCR5LMNA | |
| SCHEMBL5328378 | 0.84 | DRD2 (0.63) | DRD2ADRA1A | |
| SCHEMBL5394993 | 0.81 | CHRM2 (0.47) | DRD2ADRA1ACHRM2CCR5CHRM1 | |
| SCHEMBL5321989 | 0.80 | DRD2 (0.48) | DRD2ADRA1A | |
| SCHEMBL5324720 | 0.79 | DRD2 (0.47) | DRD2ADRA1ALMNA | |
| SCHEMBL4617822 | 0.79 | DRD2 (0.68) | DRD2ADRA1A | |
| SCHEMBL5343799 | 0.79 | DRD2 (0.48) | DRD2ADRA1A | |
| SCHEMBL5324511 | 0.79 | DRD2 (0.49) | DRD2ADRA1A | |
| SCHEMBL5323016 | 0.78 | DRD2 (0.46) | DRD2ADRA1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007114916-A2 | ARYLBENZYLPIPERIDINE COMPOUNDS | H. LUNDBECK A/S (DK) | 2007-10-11 | — | — | WO | claimed |