Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 3/20 | 0.41 |
| ▸ | CA5A | P35218 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320292 | 0.85 | DRD2 (0.44) | DRD2ADRA1AKMT2AMEN1DRD4 | |
| SCHEMBL5394994 | 0.84 | DRD2 (0.46) | DRD2ADRA1AKMT2AMEN1CA12 | |
| SCHEMBL5328378 | 0.83 | DRD2 (0.63) | DRD2ADRA1AKMT2AMEN1CA12 | |
| SCHEMBL5324921 | 0.81 | ALDH1A1 (0.41) | DRD2ADRA1AKMT2AMEN1ALDH1A1 | |
| SCHEMBL5319996 | 0.79 | DRD2 (0.52) | DRD2ADRA1AKMT2AMEN1DRD4 | |
| SCHEMBL4811463 | 0.75 | DRD2 (0.47) | DRD2ADRA1AKMT2AMEN1CA12 | |
| SCHEMBL4810317 | 0.74 | DRD2 (0.52) | DRD2ADRA1AKMT2AMEN1ALDH1A1 | |
| SCHEMBL4617548 | 0.73 | DRD2 (0.61) | DRD2ADRA1A | |
| SCHEMBL4811543 | 0.73 | LMNA (0.46) | DRD2ADRA1AKMT2AMEN1CA12 | |
| SCHEMBL5322187 | 0.73 | DRD2 (0.57) | DRD2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007114916-A2 | ARYLBENZYLPIPERIDINE COMPOUNDS | H. LUNDBECK A/S (DK) | 2007-10-11 | — | — | WO | claimed |
| WO-2007114916-A2 | ARYLBENZYLPIPERIDINE COMPOUNDS | H. LUNDBECK A/S (DK) | 2007-10-11 | — | — | WO | disclosed |