Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 1.00 |
| ▸ | DRD4 | P21917 | 2/20 | 1.00 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3900412 | 0.98 | DRD2 (0.96) | DRD2DRD4ESR1ESR2DRD1 | |
| SCHEMBL6712764 | 0.92 | DRD2 (0.85) | DRD2DRD4ESR1ESR2DRD1 | |
| SCHEMBL29722558 | 0.88 | DRD2 (0.78) | DRD2DRD4ESR1ESR2DRD1 | |
| SCHEMBL532839 | 0.88 | DRD2 (0.78) | DRD2DRD4ESR1ESR2DRD1 | |
| SCHEMBL27462116 | 0.88 | DRD2 (0.77) | DRD2DRD4ESR1ESR2KDM4E | |
| SCHEMBL6247150 | 0.86 | DRD2 (0.75) | DRD2DRD4ESR1ESR2DRD1 | |
| Bromide SCHEMBL3182004 | 0.84 | DRD2 (0.72) | DRD2DRD4ESR1ESR2DRD1 | |
| SCHEMBL27572419 | 0.84 | DRD2 (0.72) | DRD2DRD4ESR1ESR2KDM4E | |
| SCHEMBL33917 | 0.83 | DRD2 (0.70) | DRD2DRD4ESR2DRD1DRD5 | |
| SCHEMBL29378459 | 0.83 | DRD2 (0.70) | DRD2DRD4ESR2DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 365 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658989-A | Polymerizable photoisomerization donor-acceptor Stenhaus adduct and preparation method and application thereof | 北京大学 | 2024-03-08 | — | — | CN | claimed |
| CN-115353478-A | Preparation method of indole compound | 南京工业大学 | 2022-11-18 | — | — | CN | claimed |
| EP-2623093-B1 | DYE FOR KERATIN FIBERS USING BILIRUBIN OXIDASE AND INDOLE DERIVATIVES | AMANO ENZYME INC (JP) | 2016-05-25 | — | — | EP | claimed |
| US-20140359950-A1 | DYEING OF KERATIN FIBERS USING INDOLE ANALOGUE | AMANO ENZYME INC. (JP) | 2014-12-11 | — | — | US | claimed |
| US-20040231067-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses | L'OREAL (FR) | 2004-11-25 | — | — | US | claimed |
| US-4013404-A | Method of dyeing hair with indolines, indoles and indazoles | AMERICAN CYANAMID COMPANY (US) | 1977-03-22 | — | — | US | claimed |
| CN-116145156-B | Indoline compound preparation method based on organic electronic synthesis | 六盘水师范学院 | 2026-05-15 | — | — | CN | disclosed |
| EP-3113753-B2 | AQUEOUS OXIDIZING COMPOSITION FOR HAIR | KAO GERMANY GMBH (DE) | 2026-03-18 | — | — | EP | disclosed |
| CN-117658989-A | Polymerizable photoisomerization donor-acceptor Stenhaus adduct and preparation method and application thereof | 北京大学 | 2024-03-08 | — | — | CN | disclosed |
| US-11912719-B2 | Substituted isoquinolines as rock kinase inhibitors | CERVELLO THERAPEUTICS, LLC. (US) | 2024-02-27 | — | — | US | disclosed |
| US-11912719-B2 | Substituted isoquinolines as rock kinase inhibitors | CERVELLO THERAPEUTICS, LLC. (US) | 2024-02-27 | — | — | US | disclosed |
| CN-117487065-A | Photo-induced deformation liquid crystal polymer film and preparation method and application thereof | 北京大学 | 2024-02-02 | — | — | CN | disclosed |
| CN-115353478-B | Preparation method of indole compound | 南京工业大学 | 2023-10-27 | — | — | CN | disclosed |
| EP-0746554-A1 | 4-HETEROCYCLYL-SUBSTITUTED QUINAZOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS ANTI-CANCER AGENTS | PFIZER INC. (US) | 1996-12-11 | — | — | EP | disclosed |
| WO-1996022089-A1 | p-HETEROATOM-SUBSTITUTED PHENOLS AND USES THEREOF | RESEARCH DEVELOPMENT FOUNDATION (US) | 1996-07-25 | — | — | WO | disclosed |
| WO-1995023141-A1 | 4-HETEROCYCLYL-SUBSTITUTED QUINAZOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS ANTI-CANCER AGENTS | PFIZER INC. (US) | 1995-08-31 | — | — | WO | disclosed |
| EP-0269321-B1 | LIQUID CRYSTAL COPOLYESTERS HAVING A BLOCKED TERMINAL OF ITS MOLECULAR CHAIN | POLYPLASTICS CO. LTD. (JP) | 1992-08-12 | — | — | EP | disclosed |
| US-4904752-A | Liquid crystal copolyester having blocked molecular chain terminal | POLYPLASTICS CO., LTD. (JP) | 1990-02-27 | — | — | US | disclosed |
| EP-0269321-A2 | Liquid crystal copolyesters having a blocked terminal of its molecular chain | POLYPLASTICS CO. LTD. (JP) | 1988-06-01 | — | — | EP | disclosed |
| US-4013404-A | Method of dyeing hair with indolines, indoles and indazoles | AMERICAN CYANAMID COMPANY (US) | 1977-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11912719-B2 | Substituted isoquinolines as rock kinase inhibitors | ROCK1, ROCK2, CIT | DRD2 3508/4885DRD4 3772/4885ESR1 4817/4885 |
| US-20040231067-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses | KRT18, CDC73, PYCR1 | DRD2 611/4885DRD4 537/4885ESR1 3898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.