Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 6/20 | 0.55 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.55 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCND3 | P30281 | 1/20 | 0.44 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | VKORC1 | Q9BQB6 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | PCSK7 | Q16549 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23815847 | 0.71 | CREBBP (1.00) | CREBBPBRD9BRPF1HTTKDM4E | |
| SCHEMBL8481500 | 0.70 | HTT (0.75) | CREBBPBRD9BRPF1HTTKDM4E | |
| SCHEMBL11699012 | 0.70 | NQO1 (0.56) | CA12CA9MAOBKDM4EALDH1A1 | |
| SCHEMBL669375 | 0.69 | MAOB (0.70) | CA12CA9MAOBKDM4EALDH1A1 | |
| SCHEMBL29466790 | 0.69 | MAOB (0.70) | CA12CA9MAOBKDM4EALDH1A1 | |
| SCHEMBL3238254 | 0.69 | CREBBP (0.53) | CREBBPBRD9BRPF1HTTKDM4E | |
| SCHEMBL1333179 | 0.68 | HTT (0.54) | CREBBPBRD9BRPF1HTTKDM4E | |
| SCHEMBL3527681 | 0.68 | CA12 (1.00) | CA12CA9HTTKDM4EALDH1A1 | |
| SCHEMBL30933370 | 0.68 | CA12 (1.00) | CA12CA9HTTKDM4EALDH1A1 | |
| SCHEMBL27790298 | 0.67 | MAOB (0.72) | CA12CA9HTTMAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | claimed |
| WO-2007047579-A2 | A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-04-26 | — | — | WO | claimed |