Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.51 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28120658 | 0.84 | KMT2A (0.41) | HTTPOLBKDM4ERAB9AALDH1A1 | |
| SCHEMBL6123415 | 0.82 | KDM4E (0.41) | HTTPOLBKDM4ERAB9AALDH1A1 | |
| SCHEMBL887130 | 0.81 | CREBBP (0.55) | HTTPOLBKDM4ERAB9AALDH1A1 | |
| SCHEMBL887129 | 0.81 | HTT (0.54) | HTTPOLBKDM4ERAB9AALDH1A1 | |
| SCHEMBL10842060 | 0.80 | KMT2A (0.67) | POLBKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL27617492 | 0.80 | PKM (0.48) | POLBKDM4ERAB9AALDH1A1CREBBP | |
| SCHEMBL4207590 | 0.79 | CREBBP (0.63) | HTTPOLBKDM4ERAB9AALDH1A1 | |
| SCHEMBL13806317 | 0.79 | POLB (0.54) | HTTPOLBKDM4ERAB9AALDH1A1 | |
| SCHEMBL29037094 | 0.79 | NOTUM (0.62) | HTTPOLBKDM4ERAB9AALDH1A1 | |
| SCHEMBL26170754 | 0.79 | HTT (0.53) | HTTPOLBKDM4ERAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057625-B | C2-acyloxy-3-indolinone derivative and preparation method and application thereof | 五邑大学 | 2023-11-24 | — | — | CN | claimed |
| CN-114057625-A | C2-acyloxy-3-indolinone derivative and preparation method and application thereof | 五邑大学 | 2022-02-18 | — | — | CN | claimed |
| CN-110922350-B | N-acetyl-3-oxyindole compound and construction method of C-O bond at C2 position thereof | 贵州医科大学 | 2021-09-28 | — | — | CN | claimed |
| CN-110922350-A | N-acetyl-3-oxyindole compound and construction method of C-O bond at C2 position thereof | 贵州医科大学 | 2020-03-27 | — | — | CN | claimed |
| EP-2379549-B1 | 7-AZAINDIRUBINS, 7'-AZAINDIRUBINS, 7-7'-DIAZAINDIRUBIN AND THE CORRESPONDING 3'-OXIME ETHER DERIVATES: PRODUCTION THEREOF, THEIR PRODUCTION AND USE AS A MEDICAMENT | EISENBRAND GERHARD (DE) | 2016-09-21 | — | — | EP | claimed |
| US-20140235868-A1 | NOVEL ANTITHROMBOTIC AND ANTIATHEROSCLEROTIC AGENT AND METHOD FOR PRODUCING SAME (VARIANTS) | PROTON OOO (RU) | 2014-08-21 | — | — | US | claimed |
| EP-2738167-A2 | NOVEL ANTITHROMBOTIC AND ANTIATHEROSCLEROTIC AGENT AND METHOD FOR PRODUCING SAME (VARIANTS) | Proton OOO (RU) | 2014-06-04 | — | — | EP | claimed |
| WO-2013045702-A2 | DYE COMPOSITION COMPRISING A NON-GLYCOSYL IRIDOID COMPOUND AND A SPECIFIC NUCLEOPHILE OR AN AMINO OR THIO POLYMER, DYEING PROCESS, AND DEVICE THEREFOR | L'OREAL (FR) | 2013-04-04 | — | — | WO | claimed |
| EP-2379549-A1 | 7-AZAINDIRUBINS, 7'AZAINDIRUBINS, 7,7'-DIAZAINDIRUBINS AND THE CORRESPONDING 3'-OXIME ETHER DERIVATIVES THEREOF, THEIR PRODUCTION AND USE AS A MEDICAMENT | Eisenbrand, Gerhard (DE) | 2011-10-26 | — | — | EP | claimed |
| US-20100240070-A1 | Nonseparation Assay Methods Using Peroxide Generating Enzymes | BECKMAN COULTER, INC. (US) | 2010-09-23 | — | — | US | claimed |
| WO-2010072399-A1 | 7-AZAINDIRUBINS, 7'AZAINDIRUBINS, 7,7'-DIAZAINDIRUBINS AND THE CORRESPONDING 3'-OXIME ETHER DERIVATIVES THEREOF, THEIR PRODUCTION AND USE AS A MEDICAMENT | EISENBRAND GERHARD (DE) | 2010-07-01 | — | — | WO | claimed |
| EP-2199292-A1 | 7-azaindirubins, 7'-azaindirubins, 7-7'-diazaindirubin and the corresponding 3'-oxime ether derivates: production thereof, their production and use as a medicament | Technische Universität Kaiserlautern (DE) | 2010-06-23 | — | — | EP | claimed |
| WO-2009062027-A1 | NONSEPARATION ASSAY METHODS USING PEROXIDE GENERATING ENZYMES | BECKMAN COULTER, INC. (US) | 2009-05-14 | — | — | WO | claimed |
| JP-60032795-A | — | — | None | — | — | JP | disclosed |
| US-20250044306-A1 | Methods for Determining Opioid Responsiveness in the Treatment of Pain | EAST CAROLINA UNIVERSITY | 2025-02-06 | — | — | US | disclosed |
| US-20250027882-A1 | POLYMER DYE FOR DETECTING HYDROGEN PEROXIDE AND HYDROGEN PEROXIDE DETECTING MATERIAL | CANON KK (JP) | 2025-01-23 | — | — | US | disclosed |
| CN-1078460-A | The method for making of hydrazone derivative and application | SUMITOMO CHEMICAL CO (JP) | 1993-11-17 | — | — | CN | disclosed |
| EP-0567138-A2 | Hydrazone derivatives, process for producing the same, insecticides and/or acaricides containing the same as active ingredient and intermediate compounds thereof | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1993-10-27 | — | — | EP | disclosed |
| EP-0338499-A2 | Stabilized highly unsaturated fatty acids and derivatives of such acids | NABISCO BRANDS, INC. (US) | 1989-10-25 | — | — | EP | disclosed |
| JP-S6032795-A | NOVEL SUBSTRATE FOR MEASURING ACTIVITY OF PHOSPHODIESTERASE | AOYANAGI SHOHEI | 1985-02-19 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140235868-A1 | NOVEL ANTITHROMBOTIC AND ANTIATHEROSCLEROTIC AGENT AND METHOD FOR PRODUCING SAME (VARIANTS) | GUCY1B1, GUCY1A1, GUCY1A2 | HTT 4356/4885POLB 3087/4885KDM4E 1820/4885 |
| US-20250027882-A1 | POLYMER DYE FOR DETECTING HYDROGEN PEROXIDE AND HYDROGEN PEROXIDE DETECTING MATERIAL | MPO, GPX4, LPO | HTT 895/4885POLB 154/4885KDM4E 3244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.