SCHEMBL5328647

SCHEMBL5328647

CSCCC(OC(=O)C(CO)C(=O)O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
RNPEP Q9H4A4 1/20 0.43
FOLH1 Q04609 1/20 0.34
CYP2C9 P11712 1/20 0.33
LMNA P02545 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
METAP2 P50579 1/20 0.30
METAP1 P53582 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5329279 0.84 RNPEP (0.31) RNPEP
SCHEMBL5330977 0.83 TSHR (0.34) TSHRMETAP2METAP1
SCHEMBL28637319 0.82 RNPEP (0.46) RNPEPFOLH1LMNAMAPK1METAP2
SCHEMBL5329985 0.82 BHMT (0.32)
SCHEMBL23079505 0.81 RNPEP (0.44) RNPEPFOLH1LMNAMAPK1METAP2
SCHEMBL4953075 0.81 RNPEP (0.44) RNPEPFOLH1CYP2C9LMNATSHR
SCHEMBL4949335 0.81 RNPEP (0.44) RNPEPFOLH1CYP2C9LMNAMAPK1
SCHEMBL5325063 0.80 MAPT (0.33) CYP2C9MAPK1
SCHEMBL4954245 0.79 RNPEP (0.46) RNPEPFOLH1CYP2C9LMNAMAPK1
SCHEMBL9332345 0.78 RNPEP (0.48) RNPEPFOLH1LMNATSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007147155-A1 POLYOL ESTER COMPOUNDS NOVUS INTERNATIONAL INC. (US) 2007-12-21 WO disclosed
US-20070292485-A1 POLYOL ESTER COMPOUNDS NOVUS INTERNATIONAL INC. (US) 2007-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070292485-A1 POLYOL ESTER COMPOUNDS PNLIP, ELOVL1, ELOVL5 RNPEP 3086/4885FOLH1 1682/4885CYP2C9 1149/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.