Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 4/20 | 0.33 |
| ▸ | METAP1 | P53582 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5329985 | 0.89 | BHMT (0.32) | — | |
| SCHEMBL5325063 | 0.86 | MAPT (0.33) | — | |
| SCHEMBL5328647 | 0.83 | RNPEP (0.43) | TSHRMETAP2METAP1 | |
| SCHEMBL5328473 | 0.83 | OR51E2 (0.30) | — | |
| SCHEMBL4954373 | 0.82 | METAP2 (0.37) | TSHRMETAP2METAP1 | |
| SCHEMBL4954479 | 0.82 | METAP2 (0.40) | TSHRMETAP2METAP1 | |
| SCHEMBL4953978 | 0.80 | TSHR (0.36) | TSHRMETAP2METAP1 | |
| SCHEMBL4953747 | 0.80 | TSHR (0.38) | TSHRMETAP2METAP1 | |
| SCHEMBL4951805 | 0.78 | TSHR (0.37) | TSHRMETAP2METAP1 | |
| SCHEMBL5328136 | 0.77 | METAP2 (0.33) | METAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007147155-A1 | POLYOL ESTER COMPOUNDS | NOVUS INTERNATIONAL INC. (US) | 2007-12-21 | — | — | WO | disclosed |
| US-20070292485-A1 | POLYOL ESTER COMPOUNDS | NOVUS INTERNATIONAL INC. (US) | 2007-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070292485-A1 | POLYOL ESTER COMPOUNDS | PNLIP, ELOVL1, ELOVL5 | TSHR 4149/4885METAP2 2666/4885METAP1 3714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.