Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | RARB | P10826 | 5/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7519845 | 0.85 | ALDH1A1 (0.64) | ALDH1A1GLAPOLBTDP1L3MBTL1 | |
| SCHEMBL5330366 | 0.82 | PARP10 (0.49) | ALDH1A1POLBTDP1L3MBTL1TSHR | |
| SCHEMBL26455401 | 0.81 | ALDH1A1 (0.48) | ALDH1A1GLAPOLBTDP1L3MBTL1 | |
| SCHEMBL6294879 | 0.81 | ALDH1A1 (0.48) | ALDH1A1GLAPOLBTDP1L3MBTL1 | |
| SCHEMBL6223194 | 0.81 | ALDH1A1 (0.48) | ALDH1A1GLAPOLBTDP1L3MBTL1 | |
| SCHEMBL5358981 | 0.80 | ALDH1A1 (0.37) | ALDH1A1TSHRKMT2A | |
| SCHEMBL27719508 | 0.79 | ALDH1A1 (0.65) | ALDH1A1TDP1TSHRKMT2ASMN1; SMN2 | |
| Terephthalic Acid SCHEMBL28348573 | 0.79 | ALDH1A1 (0.54) | ALDH1A1TP53TSHRKMT2ASMN1; SMN2 | |
| Terephthalic Acid SCHEMBL1482407 | 0.78 | TSHR (0.71) | ALDH1A1TP53TSHRSMN1; SMN2RARB | |
| Alcohol SCHEMBL28456385 | 0.78 | ALDH1A1 (0.79) | ALDH1A1GLAPOLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007130499-A2 | ANTIVIRAL AGENTS | VIROBAY, INC. (US) | 2007-11-15 | — | — | WO | claimed |
| CN-101253151-A | GPCR agonists | PROSIDION LTD (GB) | 2008-08-27 | — | — | CN | disclosed |
| WO-2007130499-A2 | ANTIVIRAL AGENTS | VIROBAY, INC. (US) | 2007-11-15 | — | — | WO | disclosed |