Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.49 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7523315 | 0.86 | PARP10 (0.53) | PARP10PARP3MAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5328850 | 0.82 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2CA2KMT2ARAB9A | |
| SCHEMBL14782316 | 0.82 | PARP10 (0.50) | PARP10PARP3ALDH1A1PARP4PARP1 | |
| SCHEMBL13989067 | 0.81 | SAE1 (0.46) | PARP10PARP3MAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9902871 | 0.79 | PARP10 (0.55) | PARP10PARP3ALDH1A1PARP4PARP1 | |
| SCHEMBL3405671 | 0.79 | PARP10 (0.44) | PARP10PARP3ALDH1A1PARP4PARP1 | |
| SCHEMBL5358981 | 0.78 | ALDH1A1 (0.37) | ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL27719508 | 0.78 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2CA1CA2CYP2C9 | |
| SCHEMBL27687171 | 0.76 | PARP10 (0.47) | PARP10PARP3ALDH1A1SMN1; SMN2PARP4 | |
| SCHEMBL317442 | 0.74 | PARP10 (0.77) | PARP10PARP3ALDH1A1PARP4PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007130499-A2 | ANTIVIRAL AGENTS | VIROBAY, INC. (US) | 2007-11-15 | — | — | WO | claimed |
| WO-2007130499-A2 | ANTIVIRAL AGENTS | VIROBAY, INC. (US) | 2007-11-15 | — | — | WO | disclosed |