Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 12/20 | 0.48 |
| ▸ | RORC | P51449 | 6/20 | 0.42 |
| ▸ | THRA | P10827 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5330306 | 0.90 | THRB (0.43) | THRBRORCTHRAGAA | |
| SCHEMBL5323878 | 0.88 | RORC (0.55) | THRBRORCTHRA | |
| SCHEMBL5327796 | 0.86 | THRB (0.64) | THRBTHRA | |
| SCHEMBL7555866 | 0.79 | THRB (0.47) | THRBRORCTHRA | |
| SCHEMBL5327815 | 0.79 | THRB (0.53) | THRBTHRA | |
| SCHEMBL5326865 | 0.79 | RORC (0.46) | THRBRORCTHRAGAANPBWR1 | |
| SCHEMBL7597002 | 0.78 | THRB (0.47) | THRBRORCTHRAMCHR1 | |
| SCHEMBL5328904 | 0.78 | THRB (0.50) | THRBRORCTHRANPBWR1MCHR1 | |
| SCHEMBL5326041 | 0.74 | THRB (0.57) | THRBTHRA | |
| SCHEMBL282017 | 0.73 | THRB (0.53) | THRBRORCTHRAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007132475-A1 | SELECTIVE TR-BETA 1 AGONIST | CADILA HEALTHCARE LIMITED (IN) | 2007-11-22 | — | — | WO | claimed |
| WO-2007132475-A1 | SELECTIVE TR-BETA 1 AGONIST | CADILA HEALTHCARE LIMITED (IN) | 2007-11-22 | — | — | WO | disclosed |