SCHEMBL5328960

SCHEMBL5328960

COc1ccccc1C(F)=C(F)F

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA12 O43570 1/20 0.50
CA4 P22748 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CTSD P07339 1/20 0.48
NPC1 O15118 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
TP53 P04637 1/20 0.46
TSHR P16473 1/20 0.46
STAT3 P40763 1/20 0.46
RAB9A P51151 2/20 0.45
GAA P10253 1/20 0.45
ABCG2 Q9UNQ0 1/20 0.44
HTT P42858 2/20 0.44
LMNA P02545 1/20 0.44
ENPP2 Q13822 1/20 0.43
KCNK3 O14649 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16934145 0.85 CA1 (0.48) CA1CA2CA12CA4CA7
SCHEMBL1705501 0.82 CA1 (0.55) CA1CA2CA12CA4CA7
SCHEMBL29221498 0.82 HTT (0.42) CA1CA2CA12CA4CA7
SCHEMBL2046808 0.78 CA1 (0.50) CA1CA2CA12CA4CA7
SCHEMBL23391001 0.78 CTSD (0.58) CTSDNPC1SMN1; SMN2STAT3RAB9A
SCHEMBL16933707 0.77 CA1 (0.48) CA1CA2CA12CA4CA7
SCHEMBL16933705 0.77 CA1 (0.48) CA1CA2CA12CA4CA7
SCHEMBL157181 0.77 CA1 (0.60) CA1CA2CA12CA4CA7
SCHEMBL11105353 0.76 CTSD (0.47) CA1CA2CA12CA4CA7
SCHEMBL726749 0.75 ALDH1A1 (0.38) CA1CA2CA12CA4CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7300984-B2 Process for preparing graft copolymers and membranes formed therefrom BALLARD POWER SYSTEMS INC. (CA) 2007-11-27 US claimed
EP-1421126-B1 PROCESS FOR PREPARING GRAFT COPOLYMER MEMBRANES BALLARD POWER SYSTEMS (CA) 2007-03-14 EP claimed
US-20060079594-A1 Process for preparing graft copolymer membranes STONE CHARLES 2006-04-13 US claimed
US-20050165167-A1 Process for preparing graft copolymers and membranes formed therefrom BDF IP HOLDINGS LTD. (CA) 2005-07-28 US claimed
US-6828386-B2 Exposure a fluorostyrene polymer to sulfur trioxide vapors; swelling BALLARD POWER SYSTEMS INC. (CA) 2004-12-07 US claimed
EP-1421126-A1 PROCESS FOR PREPARING GRAFT COPOLYMER MEMBRANES BALLARD POWER SYSTEMS INC. (CA) 2004-05-26 EP claimed
US-20040059015-A1 Process for preparing graft copolymers and membranes formed therefrom BALLARD POWER SYSTEMS INC. (CA) 2004-03-25 US claimed
US-20040016693-A1 Process for preparing graft copolymer membranes BALLARD POWER SYSTEMS INC. (CA) 2004-01-29 US claimed
US-20040009305-A1 Process for preparing graft copolymer membranes BALLARD POWER SYSTEMS INC. (CA) 2004-01-15 US claimed
WO-2003018655-A1 PROCESS FOR PREPARING GRAFT COPOLYMER MEMBRANES BALLARD POWER SYSTEMS INC. (CA) 2003-03-06 WO claimed
CN-107235875-A A kind of method for synthesizing 1,2,2 trifluoro-ethylene sulfide compounds 福州大学 2017-10-10 CN disclosed
CN-103373897-B Preparation method of trifluorostyrene compound SHANGHAI INST ORGANIC CHEM 2015-07-08 CN disclosed
US-7300984-B2 Process for preparing graft copolymers and membranes formed therefrom BALLARD POWER SYSTEMS INC. (CA) 2007-11-27 US disclosed
EP-1421126-B1 PROCESS FOR PREPARING GRAFT COPOLYMER MEMBRANES BALLARD POWER SYSTEMS (CA) 2007-03-14 EP disclosed
US-20060079594-A1 Process for preparing graft copolymer membranes STONE CHARLES 2006-04-13 US disclosed
US-20040059015-A1 Process for preparing graft copolymers and membranes formed therefrom BALLARD POWER SYSTEMS INC. (CA) 2004-03-25 US disclosed
US-20040016693-A1 Process for preparing graft copolymer membranes BALLARD POWER SYSTEMS INC. (CA) 2004-01-29 US disclosed
US-20040009305-A1 Process for preparing graft copolymer membranes BALLARD POWER SYSTEMS INC. (CA) 2004-01-15 US disclosed
WO-2003018654-A1 PROCESS FOR PREPARING GRAFT COPOLYMER MEMBRANES BALLARD POWER SYSTEMS INC. (CA) 2003-03-06 WO disclosed
WO-2003018655-A1 PROCESS FOR PREPARING GRAFT COPOLYMER MEMBRANES BALLARD POWER SYSTEMS INC. (CA) 2003-03-06 WO disclosed