Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA4 | P22748 | 3/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28898518 | 0.84 | ALDH1A1 (0.67) | ALDH1A1ALOX15KDM4EHPGDCA12 | |
| SCHEMBL970209 | 0.83 | CES2 (0.54) | ALDH1A1ALOX15CES2CES1HPGD | |
| SCHEMBL28457557 | 0.83 | HPGD (0.48) | ALDH1A1ALOX15KDM4EHPGDCA12 | |
| SCHEMBL15568584 | 0.83 | ALDH1A1 (0.56) | ALDH1A1ALOX15CES2CES1KDM4E | |
| SCHEMBL8896144 | 0.81 | NPC1 (0.38) | ALDH1A1HPGDSMN1; SMN2NPC1LMNA | |
| SCHEMBL5328450 | 0.81 | ACHE (0.43) | HPGDSMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL4452338 | 0.79 | CES2 (0.31) | CES2CES1 | |
| SCHEMBL21218733 | 0.79 | CES2 (0.41) | ALDH1A1ALOX15CES2CES1HPGD | |
| SCHEMBL29221498 | 0.79 | HTT (0.42) | ALDH1A1KDM4EHPGDCA12CA2 | |
| SCHEMBL5698198 | 0.78 | AKR1C1 (0.38) | ALDH1A1KDM4EHPGDMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790091-A | Replace bis- (trifluoro vinyl) benzene compounds | 东曹精细化工株式会社 | 2019-05-21 | — | — | CN | claimed |
| JP-4796055-B2 | — | — | 2011-10-19 | — | — | JP | claimed |
| US-7829603-B2 | Stable trifluorostyrene containing compounds grafted to base polymers, and their use as polymer electrolyte membranes | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-11-09 | — | — | US | claimed |
| JP-2007536391-A | — | — | 2007-12-13 | — | — | JP | claimed |
| US-20070208092-A1 | Stable Trifluorostyrene Containing Compounds Grafted To Base Polymers, And Their Use As Polymer Electrolyte Membranes | U.S. DEPARTMENT OF ENERGY | 2007-09-06 | — | — | US | claimed |
| WO-2005113621-A1 | STABLE TRIFLUOROSTYRENE CONTAINING COMPOUNDS GRAFTED TO BASE POLYMERS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2005-12-01 | — | — | WO | claimed |
| US-10654779-B2 | Substituted bis(trifluorovinyl)benzene compound | TOSOH FINECHEM CORPORATION (JP) | 2020-05-19 | — | — | US | disclosed |
| CN-109790091-A | Replace bis- (trifluoro vinyl) benzene compounds | 东曹精细化工株式会社 | 2019-05-21 | — | — | CN | disclosed |
| CN-109790091-A | Replace bis- (trifluoro vinyl) benzene compounds | 东曹精细化工株式会社 | 2019-05-21 | — | — | CN | disclosed |
| CN-109790091-A | Replace bis- (trifluoro vinyl) benzene compounds | 东曹精细化工株式会社 | 2019-05-21 | — | — | CN | disclosed |
| US-4506035-A | IMPROVING THE WETABILITY OF DIAPHRAGMS BY GRAFT COPOLYMERIZATION OF CARBOXY-CONTAINING MONOMERS; ELECTROLYTIC CELLS | ICI AUSTRALIA LIMITED (AU) | 1985-03-19 | — | — | US | disclosed |
| US-4385130-A | IRRADIATION GRAFT POLYMERIZED PERMSELECTIVE MEMBRANES FOR ELECTROLYSIS CELLS | ICI AUSTRALIA LIMITED (AU) | 1983-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10654779-B2 | Substituted bis(trifluorovinyl)benzene compound | TCF7L2, AFF1, TYR | ALDH1A1 1738/4885ALOX15 2885/4885CES2 2706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.