Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2672524 | 0.92 | MMP8 (0.50) | MMP8CYP2A6RAB9AMAPTTDP1 | |
| SCHEMBL4028528 | 0.90 | MMP8 (0.51) | MMP8CYP2A6RAB9AMAPTTDP1 | |
| SCHEMBL533901 | 0.87 | MMP8 (0.46) | MMP8CYP2A6RAB9AMAPTTDP1 | |
| SCHEMBL4071057 | 0.86 | LOXL2 (0.50) | CYP2A6RAB9AMAPTLOXL2MAOB | |
| SCHEMBL5109806 | 0.84 | DPP4 (0.47) | CYP2A6RAB9AMAPTTDP1LOXL2 | |
| SCHEMBL6161194 | 0.84 | DPP4 (0.47) | CYP2A6RAB9AMAPTTDP1LOXL2 | |
| SCHEMBL10707875 | 0.83 | PDCD1 (0.46) | MMP8TDP1MAOBTSHRMAPK1 | |
| SCHEMBL5326604 | 0.83 | MMP8 (0.53) | MMP8MAPTTDP1SMN1; SMN2TSHR | |
| SCHEMBL2050344 | 0.83 | MMP8 (0.53) | MMP8RAB9AMAPTTDP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5148984 | 0.82 | DPP4 (0.46) | CYP2A6RAB9AMAPTTDP1LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007144625-A1 | 2-OXO-2H-CHROMENE COMPOUNDS | ARGENTA DISCOVERY LIMITED (GB) | 2007-12-21 | — | — | WO | disclosed |