Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PAM | P19021 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5330368 | 0.90 | TBXAS1 (0.41) | ALDH1A1CYP2A6HTTCYP1A2CYP2D6 | |
| SCHEMBL4986436 | 0.88 | TBXAS1 (0.47) | ALDH1A1CYP2A6HTTCYP1A2CYP2D6 | |
| SCHEMBL7916077 | 0.86 | TBXAS1 (0.46) | CYP1A2KDM4EMAPTLMNAHDAC3 | |
| SCHEMBL4990558 | 0.86 | TBXAS1 (0.46) | CYP1A2KDM4EMAPTLMNAHDAC3 | |
| SCHEMBL6037485 | 0.83 | ALDH1A1 (0.52) | ALDH1A1CYP2A6CYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL2541681 | 0.80 | PAM (0.55) | ALDH1A1HTTCYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL2401094 | 0.80 | ALDH1A1 (0.53) | ALDH1A1CYP1A2CYP2D6PKMLMNA | |
| SCHEMBL176807 | 0.78 | PAM (0.47) | ALDH1A1CYP2A6HTTCYP1A2CYP2D6 | |
| SCHEMBL3465968 | 0.78 | TBXAS1 (0.49) | ALDH1A1CYP1A2CYP2D6SMN1; SMN2KDM4E | |
| SCHEMBL12482498 | 0.78 | TDP1 (0.55) | ALDH1A1HTTCYP1A2SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070287699-A1 | ANTIVIRAL AGENTS | VIROBAY, INC. (US) | 2007-12-13 | — | — | US | claimed |
| WO-2007130499-A2 | ANTIVIRAL AGENTS | VIROBAY, INC. (US) | 2007-11-15 | — | — | WO | claimed |
| US-6875743-B1 | Cell adhesion inhibitors | BIOGEN, INC. (US) | 2005-04-05 | — | — | US | claimed |
| US-20070287699-A1 | ANTIVIRAL AGENTS | VIROBAY, INC. (US) | 2007-12-13 | — | — | US | disclosed |
| WO-2007130499-A2 | ANTIVIRAL AGENTS | VIROBAY, INC. (US) | 2007-11-15 | — | — | WO | disclosed |
| US-4611075-A | Preparation of 4-(α,α-dihydrocarbyl-α-cyano-methyl)phenols | ETHYL CORPORATION (US) | 1986-09-09 | — | — | US | disclosed |
| US-4537920-A | 4H-1-benzopyrans and lubricant compositions containing same | ETHYL CORPORATION (US) | 1985-08-27 | — | — | US | disclosed |
| US-4487722-A | Method of preparing 4-(α-hydrocarbyl-α-cyanomethyl)2,6-di-substituted phenols | ETHYL CORPORATION (US) | 1984-12-11 | — | — | US | disclosed |
| US-4485051-A | Preparation of 4-(α-hydrocarbyl-α-cyanomethyl)-2,6-di-substituted phenols | ETHYL CORPORATION (US) | 1984-11-27 | — | — | US | disclosed |
| US-4483800-A | Preparation of 4-(α-alkyl-α-cyano-methyl)-2,6-di-substituted phenols | ETHYL CORPORATION (US) | 1984-11-20 | — | — | US | disclosed |
| US-4481368-A | Process for preparing α-keto-carboxylic acids from acyl halides | ETHYL CORPORATION (US) | 1984-11-06 | — | — | US | disclosed |
| US-4481369-A | VIA TRICARBONYL(TRIPHENYLPOSPHINE) COBALTATE | ETHYL CORPORATION (US) | 1984-11-06 | — | — | US | disclosed |
| US-4082517-A | CYCLOPENTADIENYL MANGANESE ANTIKNOCK | ETHYL CORPORATION (US) | 1978-04-04 | — | — | US | disclosed |
| US-RE29488-E | CYCLOPENTADIENYL MANGANESE TRICARBONYL, CARBOXYMETHOXY-SUCCINIC ACIDS | ETHYL CORPORATION (US) | 1977-12-06 | — | — | US | disclosed |
| US-4052171-A | FUEL COMPOSITIONS AND ADDITIVE MIXTURES CONTAINING METHANETRICARBOXYLATES FOR REDUCING EXHAUST GAS CATALYST PLUGGING | ETHYL CORPORATION (US) | 1977-10-04 | — | — | US | disclosed |
| US-4005993-A | CYCLOPENTADIENYL MANGANESE TRICARBONYL, OXYALKYL-MALONIC ACIDS OR ESTERS | ETHYL CORPORATION (US) | 1977-02-01 | — | — | US | disclosed |
| US-4005992-A | CYCLOPENTADIENYL MAGNESIUM TRICARBONYL, OXYMETHYLENEMALONIC ACIDS OR ESTERS | ETHYL CORPORATION (US) | 1977-02-01 | — | — | US | disclosed |
| US-3958955-A | CYCLOPENTADIENYL MANGANESE TRICARBONYL ANTIKNOCK | ETHYL CORPORATION (US) | 1976-05-25 | — | — | US | disclosed |
| US-3950145-A | ANTIKNOCK | ETHYL CORPORATION (US) | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287699-A1 | ANTIVIRAL AGENTS | EIF2AK2, MAVS, ZC3HAV1 | ALDH1A1 1759/4885CYP2A6 2507/4885HTT 3799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.