SCHEMBL5329321

SCHEMBL5329321

Nc1cc(O)c(N)c(N)c1N

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 5/20 0.38
HSD17B10 Q99714 4/20 0.38
CYP3A4 P08684 1/20 0.38
TSHR P16473 1/20 0.35
ALDH1A1 P00352 7/20 0.35
ALOX12 P18054 3/20 0.35
HPGD P15428 2/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
GAA P10253 7/20 0.34
MAPT P10636 6/20 0.34
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
KDM4E B2RXH2 3/20 0.33
PKM P14618 2/20 0.33
PTK2 Q05397 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
POLB P06746 1/20 0.33
RAB9A P51151 1/20 0.33
HTT P42858 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30595512 1.00 ALOX15 (0.38) ALOX15HSD17B10CYP3A4TSHRALDH1A1
SCHEMBL19511839 0.83 ALDH1A1 (0.39) ALOX15HSD17B10CYP3A4TSHRALDH1A1
SCHEMBL6268650 0.79 ALOX15 (0.36) ALOX15HSD17B10CYP3A4TSHRALDH1A1
SCHEMBL9160225 0.79 ALDH1A1 (0.39) ALOX15HSD17B10CYP3A4TSHRALDH1A1
SCHEMBL7266240 0.79 ALOX15 (0.36) ALOX15HSD17B10CYP3A4TSHRALDH1A1
SCHEMBL2025359 0.75 PTK2 (0.58) ALOX15HSD17B10CYP3A4TSHRALDH1A1
SCHEMBL15600590 0.75 ALDH1A1 (0.46) ALOX15HSD17B10CYP3A4TSHRALDH1A1
SCHEMBL4961273 0.73 TSHR (0.39) ALOX15HSD17B10CYP3A4TSHRALDH1A1
SCHEMBL766082 0.73 BACE1 (0.39) ALOX15HSD17B10CYP3A4TSHRALDH1A1
SCHEMBL29433138 0.73 BACE1 (0.39) ALOX15HSD17B10CYP3A4TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3171975-B1 CATALYSTS ECONIC TECH LTD (GB) 2023-10-04 EP claimed
US-20200140610-A1 CATALYSTS ECONIC TECHNOLOGIES LTD (GB) 2020-05-07 US claimed
CN-106536048-B Catalyst and process for preparing same 埃科尼克科技有限公司 2020-05-05 CN claimed
US-20170210848-A1 Catalysts ECONIC TECHNOLOGIES LTD (GB) 2017-07-27 US claimed
EP-3171975-A1 CATALYSTS Econic Technologies Ltd (GB) 2017-05-31 EP claimed
WO-2016012785-A1 CATALYSTS ECONIC TECHNOLOGIES LTD (GB) 2016-01-28 WO claimed
EP-3171975-B1 CATALYSTS ECONIC TECH LTD (GB) 2023-10-04 EP disclosed
CN-116735573-A Cadmium ion visual detection method based on nucleic acid aptamer 天津工业大学 2023-09-12 CN disclosed
US-20200140610-A1 CATALYSTS ECONIC TECHNOLOGIES LTD (GB) 2020-05-07 US disclosed
CN-106536048-B Catalyst and process for preparing same 埃科尼克科技有限公司 2020-05-05 CN disclosed
CN-111014720-A Method and device for synthesizing nano silver on line 华北电力大学(保定) 2020-04-17 CN disclosed
US-10556988-B2 Catalysts ECONIC TECHNOLOGIES LTD (GB) 2020-02-11 US disclosed
US-20170210848-A1 Catalysts ECONIC TECHNOLOGIES LTD (GB) 2017-07-27 US disclosed
EP-3171975-A1 CATALYSTS Econic Technologies Ltd (GB) 2017-05-31 EP disclosed
CN-106536048-A Catalyst and process for preparing same 埃科尼克科技有限公司 2017-03-22 CN disclosed
WO-2016012785-A1 CATALYSTS ECONIC TECHNOLOGIES LTD (GB) 2016-01-28 WO disclosed
JP-2007169236-A TETRAKISAMINOPHENOL COMPOUND SUMITOMO BAKELITE CO LTD 2007-07-05 JP disclosed
US-20050215726-A1 Perfluoroelastomer molded article and method for producing the same NICHIAS CORPORATION (JP) 2005-09-29 US disclosed
US-20050197458-A1 Perfluoroelastomer molded article having non-sticking property to metal and method for producing the same NICHIAS CORPORATION (JP) 2005-09-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200140610-A1 CATALYSTS MLX, CA12, CA1 ALOX15 896/4885HSD17B10 2929/4885CYP3A4 585/4885
US-20170210848-A1 Catalysts MLX, CA3, CA1 ALOX15 489/4885HSD17B10 2845/4885CYP3A4 863/4885
US-10556988-B2 Catalysts MLX, CA3, CA1 ALOX15 489/4885HSD17B10 2845/4885CYP3A4 863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.