Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH2 | P48735 | 1/20 | 0.41 |
| ▸ | APOB | P04114 | 2/20 | 0.41 |
| ▸ | MTTP | P55157 | 2/20 | 0.41 |
| ▸ | NPY2R | P49146 | 2/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | TEK | Q02763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL532924 | 0.81 | NLRP3 (0.50) | LMNAMAPTKMT2AGAAKDM4E | |
| SCHEMBL533307 | 0.79 | F10 (0.43) | LMNAMEN1MAPTKMT2AGAA | |
| SCHEMBL533654 | 0.78 | LMNA (0.60) | MTTPNPY2RCREBBPLMNAAVPR1A | |
| SCHEMBL532826 | 0.78 | ALDH1A1 (0.47) | NPY2RCREBBPLMNAAVPR1AMAPT | |
| SCHEMBL532809 | 0.77 | ALDH1A1 (0.46) | NPY2RCREBBPLMNAMEN1MAPT | |
| SCHEMBL532902 | 0.72 | L3MBTL1 (0.43) | MTTPNPY2RLMNAMEN1MAPT | |
| SCHEMBL533571 | 0.71 | CNR1 (0.51) | LMNAMEN1MAPTKMT2AGAA | |
| SCHEMBL533536 | 0.71 | L3MBTL1 (0.49) | LMNAMEN1MAPTKMT2AGAA | |
| SCHEMBL5567398 | 0.71 | MAPT (0.44) | MTTPLMNAAVPR1AMEN1MAPT | |
| SCHEMBL8320252 | 0.70 | ALDH1A1 (0.46) | NPY2RCREBBPLMNAMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415760-A2 | CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2012-02-08 | — | — | EP | disclosed |