Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 11/20 | 0.37 |
| ▸ | CTSL | P07711 | 3/20 | 0.37 |
| ▸ | CTSB | P07858 | 3/20 | 0.37 |
| ▸ | CTSH | P09668 | 2/20 | 0.36 |
| ▸ | KLK7 | P49862 | 2/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5330165 | 0.79 | FOLH1 (0.39) | FOLH1 | |
| SCHEMBL5331601 | 0.79 | FAAH (0.39) | FOLH1CTSKCTSLCTSBCTSH | |
| SCHEMBL5331113 | 0.79 | TSHR (0.43) | FOLH1CNR2TSHRCTSKCTSL | |
| SCHEMBL5324777 | 0.78 | FOLH1 (0.36) | FOLH1CTSKCTSLCTSB | |
| SCHEMBL5331598 | 0.76 | POLB (0.38) | FOLH1CTSKKLK7 | |
| SCHEMBL5332601 | 0.75 | FAAH (0.37) | CTSKCTSLCTSB | |
| SCHEMBL5331118 | 0.73 | ADRB2 (0.40) | FOLH1CNR2TSHRCTSKCTSL | |
| SCHEMBL5330158 | 0.72 | GPR88 (0.35) | FOLH1CTSKKLK7 | |
| SCHEMBL5330532 | 0.71 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL5324767 | 0.71 | GPR88 (0.34) | CTSKKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007146086-A1 | CREATINE PRODRUGS, COMPOSITIONS AND USES THEREOF | XENOPORT, INC. (US) | 2007-12-21 | — | — | WO | disclosed |