Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 6/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5331057 | 0.90 | FAAH (0.38) | FAAHFOLH1SMN1; SMN2 | |
| SCHEMBL5331537 | 0.88 | TSHR (0.46) | TSHRKLK7FAAHLTA4HPOLB | |
| SCHEMBL5324604 | 0.82 | TSHR (0.46) | TSHRKLK7FAAH | |
| SCHEMBL5331118 | 0.81 | ADRB2 (0.40) | TSHRCTSLCTSBCTSKPOLB | |
| SCHEMBL5331767 | 0.80 | FAAH (0.40) | FAAH | |
| SCHEMBL5330077 | 0.79 | FOLH1 (0.40) | TSHRKLK7CTSLCTSBCTSK | |
| SCHEMBL5330532 | 0.78 | SMN1; SMN2 (0.41) | FAAHSMN1; SMN2 | |
| SCHEMBL5324557 | 0.78 | TSHR (0.46) | TSHRKLK7POLBSMN1; SMN2 | |
| SCHEMBL5324777 | 0.75 | FOLH1 (0.36) | CTSLCTSBCTSKFAAHFOLH1 | |
| SCHEMBL5331061 | 0.73 | TDP1 (0.40) | FOLH1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007146086-A1 | CREATINE PRODRUGS, COMPOSITIONS AND USES THEREOF | XENOPORT, INC. (US) | 2007-12-21 | — | — | WO | disclosed |