SCHEMBL5330203

SCHEMBL5330203

CC(=O)c1ccc(OCCOc2ccccc2C)cc1

nearest known ligand 0.74

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.74
TDP1 Q9NUW8 1/20 0.74
MAOB P27338 2/20 0.61
GAA P10253 1/20 0.60
MAPT P10636 5/20 0.56
ALDH1A1 P00352 1/20 0.56
LMNA P02545 2/20 0.55
PKM P14618 1/20 0.51
DRD2 P14416 2/20 0.51
DRD4 P21917 2/20 0.51
DRD3 P35462 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
RXRA P19793 1/20 0.50
RXRB P28702 1/20 0.50
RXRG P48443 1/20 0.50
RAB9A P51151 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5289695 0.83 L3MBTL1 (0.75) L3MBTL1MAOBGAAMAPTALDH1A1
SCHEMBL834525 0.83 L3MBTL1 (0.88) L3MBTL1MAOBGAAMAPTALDH1A1
SCHEMBL18477955 0.82 POLB (0.57) L3MBTL1TDP1MAOBGAAMAPT
SCHEMBL10707303 0.80 TDP1 (0.63) L3MBTL1TDP1GAAMAPTALDH1A1
SCHEMBL5608673 0.80 HPGD (0.62) L3MBTL1TDP1MAOBMAPTALDH1A1
SCHEMBL18477942 0.80 L3MBTL1 (0.75) L3MBTL1TDP1MAOBGAAMAPT
SCHEMBL3763522 0.80 DRD2 (0.73) L3MBTL1TDP1MAPTALDH1A1DRD2
SCHEMBL5279270 0.79 DRD2 (0.72) L3MBTL1TDP1MAPTALDH1A1PKM
SCHEMBL18477637 0.79 L3MBTL1 (0.54) L3MBTL1TDP1MAOBGAAMAPT
SCHEMBL18477946 0.78 MAOB (0.73) L3MBTL1MAOBGAAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006138653-A9 THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME NASHUA CORP (US) 2007-03-01 WO disclosed
US-20060293181-A1 Thermal recording materials and methods of making and using the same NASHUA CORPORATION 2006-12-28 US disclosed
WO-2006138653-A1 THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME NASHUA CORPORATION (US) 2006-12-28 WO disclosed
US-RE36321-E INCLUDING DIARYL DIETHER COMPOUND KANSAKI PAPER MANUFACTURING CO., LTD. (JP) 1999-09-28 US disclosed
EP-0141170-B1 HEAT-SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1987-05-13 EP disclosed
US-4531140-A Heat-sensitive recording material Kansaki Paper Manufacturing Co. Ltd. (JP) 1985-07-23 US disclosed
EP-0141170-A2 Heat-sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1985-05-15 EP disclosed