Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 1/20 | 0.60 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.60 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.60 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592141 | 0.84 | SLC6A1 (0.65) | SLC6A1SLC6A12SLC6A11SLC6A13OPRM1 | |
| Hydrochloric Acid SCHEMBL5592234 | 0.83 | SLC6A1 (0.64) | SLC6A1SLC6A12SLC6A11SLC6A13OPRM1 | |
| SCHEMBL5329926 | 0.82 | USP2 (0.48) | SLC6A1SLC6A12SLC6A11SLC6A13HSD17B10 | |
| SCHEMBL5592122 | 0.82 | SLC6A1 (0.63) | SLC6A1SLC6A12SLC6A11SLC6A13OPRM1 | |
| Hydrochloric Acid SCHEMBL5592131 | 0.81 | SLC6A1 (0.62) | SLC6A1SLC6A12SLC6A11SLC6A13OPRM1 | |
| SCHEMBL6240084 | 0.78 | DRD2 (0.71) | HSD17B10DRD2DRD3ADRA1DADRA1A | |
| SCHEMBL11808412 | 0.78 | DRD2 (0.66) | SLC6A1SLC6A12SLC6A11SLC6A13HSD17B10 | |
| Hydrochloric Acid SCHEMBL7105041 | 0.78 | DRD2 (0.70) | HSD17B10DRD2DRD3ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL11254208 | 0.76 | HTR1A (0.67) | SLC6A1SLC6A12SLC6A11SLC6A13DRD2 | |
| SCHEMBL6474802 | 0.75 | DRD2 (0.49) | HSD17B10USP2DRD2DRD3ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029156-A2 | ISOINDOLEDIONE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | claimed |
| WO-2007029156-A2 | ISOINDOLEDIONE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |