Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 3/20 | 0.60 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.58 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.58 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5598873 | 0.83 | GRIN1 (0.75) | ABCB1GRIN1GRIN2BTMEM97SIGMAR1 | |
| SCHEMBL5332230 | 0.80 | HTR7 (0.66) | — | |
| SCHEMBL12124724 | 0.79 | ALDH1A1 (0.69) | ABCB1GRIN1GRIN2BTMEM97SIGMAR1 | |
| SCHEMBL23001345 | 0.78 | ABCB1 (0.97) | ABCB1GRIN1GRIN2BTMEM97SIGMAR1 | |
| SCHEMBL10035516 | 0.77 | ALDH1A1 (0.69) | ABCB1GRIN1GRIN2BTMEM97SIGMAR1 | |
| SCHEMBL4223310 | 0.76 | ABCB1 (0.74) | ABCB1GRIN1GRIN2BTMEM97SIGMAR1 | |
| SCHEMBL10315942 | 0.76 | ABCB1 (1.00) | ABCB1GRIN1GRIN2BTMEM97SIGMAR1 | |
| SCHEMBL5330830 | 0.76 | HTR7 (0.64) | — | |
| Hydrochloric Acid SCHEMBL4223007 | 0.75 | ABCB1 (0.72) | ABCB1GRIN1GRIN2BTMEM97SIGMAR1 | |
| SCHEMBL4228297 | 0.75 | ABCB1 (0.76) | ABCB1GRIN1GRIN2BTMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029156-A2 | ISOINDOLEDIONE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | claimed |
| WO-2007029156-A2 | ISOINDOLEDIONE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |