Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 7/20 | 0.66 |
| ▸ | HTR1A | P08908 | 4/20 | 0.66 |
| ▸ | DRD3 | P35462 | 2/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5330830 | 0.96 | HTR7 (0.64) | HTR7HTR1ADRD3 | |
| SCHEMBL5333504 | 0.85 | HTR7 (0.63) | HTR7HTR1ADRD3HDAC3HDAC1 | |
| SCHEMBL5599556 | 0.81 | HTR7 (0.73) | HTR7HTR1ADRD3HDAC3HDAC1 | |
| SCHEMBL5330476 | 0.80 | ABCB1 (0.60) | — | |
| SCHEMBL7983132 | 0.80 | HTR7 (1.00) | HTR7HTR1ADRD3 | |
| Hydrochloric Acid SCHEMBL5599424 | 0.80 | DRD3 (0.74) | HTR7HTR1ADRD3HDAC3HDAC1 | |
| SCHEMBL5329808 | 0.79 | HTR7 (0.53) | HTR7HTR1ADRD3HDAC3HDAC1 | |
| SCHEMBL7983795 | 0.77 | HTR7 (0.94) | HTR7HTR1ADRD3 | |
| SCHEMBL21168596 | 0.77 | ALDH1A1 (0.61) | HTR7HTR1A | |
| SCHEMBL11836473 | 0.75 | HTR7 (0.79) | HTR7HTR1ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029156-A2 | ISOINDOLEDIONE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |