Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 9/20 | 0.64 |
| ▸ | HTR1A | P08908 | 6/20 | 0.64 |
| ▸ | DRD3 | P35462 | 4/20 | 0.64 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332230 | 0.96 | HTR7 (0.66) | HTR7HTR1ADRD3 | |
| SCHEMBL5333504 | 0.81 | HTR7 (0.63) | HTR7HTR1ADRD3DRD2HTR2A | |
| SCHEMBL7983795 | 0.81 | HTR7 (0.94) | HTR7HTR1ADRD3 | |
| SCHEMBL5335396 | 0.78 | HTR7 (0.51) | HTR7HTR1ADRD3DRD2HTR2A | |
| SCHEMBL5599281 | 0.78 | HTR7 (0.69) | HTR7HTR1ADRD3 | |
| SCHEMBL7983132 | 0.78 | HTR7 (1.00) | HTR7HTR1ADRD3 | |
| SCHEMBL5599556 | 0.76 | HTR7 (0.73) | HTR7HTR1ADRD3 | |
| SCHEMBL5330476 | 0.76 | ABCB1 (0.60) | — | |
| Hydrochloric Acid SCHEMBL5599424 | 0.75 | DRD3 (0.74) | HTR7HTR1ADRD3 | |
| SCHEMBL6475395 | 0.75 | HTR1A (0.67) | HTR7HTR1ADRD3DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029156-A2 | ISOINDOLEDIONE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |