Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14624154 | 0.89 | THRB (0.37) | THRBHTTCYP2C9PTGS2PTGS1 | |
| SCHEMBL5325697 | 0.84 | RAD51 (0.40) | THRBHTTCYP2C9PTGS2PTGS1 | |
| SCHEMBL5320985 | 0.83 | PTGS2 (0.43) | THRBHTTCYP2C9PTGS2PTGS1 | |
| SCHEMBL5331474 | 0.83 | PTGS2 (0.38) | THRBHTTCYP2C9PTGS2PTGS1 | |
| SCHEMBL5328124 | 0.82 | PTGS2 (0.37) | THRBHTTCYP2C9PTGS2PTGS1 | |
| SCHEMBL5324453 | 0.82 | CSF1R (0.40) | THRBHTTCYP2C9PTGS2PTGS1 | |
| SCHEMBL5320843 | 0.81 | DRD2 (0.44) | THRBHTTPTGS2PTGS1LMNA | |
| SCHEMBL5325596 | 0.80 | MEN1 (0.41) | HTT | |
| SCHEMBL5296183 | 0.80 | POLB (0.34) | THRBHTTCYP2C9PTGS2PTGS1 | |
| SCHEMBL14624160 | 0.80 | HTT (0.35) | THRBHTTCYP2C9PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | claimed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |