Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 3/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.42 |
| ▸ | STS | P08842 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | WNT3 | P56703 | 2/20 | 0.38 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18314687 | 1.00 | LMNA (0.47) | LMNANPSR1MMP13KMT2AMEN1 | |
| SCHEMBL5330597 | 1.00 | LMNA (0.47) | LMNANPSR1MMP13KMT2AMEN1 | |
| SCHEMBL5328714 | 0.97 | MMP13 (0.45) | LMNANPSR1MMP13KMT2AMEN1 | |
| SCHEMBL5375740 | 0.97 | MMP13 (0.45) | LMNANPSR1MMP13KMT2AMEN1 | |
| SCHEMBL5328711 | 0.97 | MMP13 (0.45) | LMNANPSR1MMP13KMT2AMEN1 | |
| SCHEMBL30259365 | 0.85 | ALDH1A1 (0.44) | LMNANPSR1MMP13KMT2AMEN1 | |
| SCHEMBL16992199 | 0.85 | F2 (0.46) | LMNAKMT2AMEN1ALDH1A1F2 | |
| SCHEMBL16992202 | 0.85 | F2 (0.46) | LMNAKMT2AMEN1ALDH1A1F2 | |
| SCHEMBL22034168 | 0.84 | MMP13 (0.45) | MMP13KMT2AMEN1ALDH1A1STS | |
| SCHEMBL22034167 | 0.84 | MMP13 (0.45) | MMP13KMT2AMEN1ALDH1A1STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039782-A1 | TETRAZOLE DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2007-04-12 | — | — | WO | disclosed |