Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | STS | P08842 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5328711 | 1.00 | MMP13 (0.45) | MMP13LMNANPSR1ALDH1A1KMT2A | |
| SCHEMBL5328714 | 1.00 | MMP13 (0.45) | MMP13LMNANPSR1ALDH1A1KMT2A | |
| SCHEMBL18314687 | 0.97 | LMNA (0.47) | MMP13LMNANPSR1ALDH1A1KMT2A | |
| SCHEMBL5330600 | 0.97 | LMNA (0.47) | MMP13LMNANPSR1ALDH1A1KMT2A | |
| SCHEMBL5330597 | 0.97 | LMNA (0.47) | MMP13LMNANPSR1ALDH1A1KMT2A | |
| SCHEMBL30259365 | 0.84 | ALDH1A1 (0.44) | MMP13LMNANPSR1ALDH1A1KMT2A | |
| SCHEMBL22034167 | 0.83 | MMP13 (0.45) | MMP13ALDH1A1KMT2AMEN1STS | |
| SCHEMBL22034168 | 0.83 | MMP13 (0.45) | MMP13ALDH1A1KMT2AMEN1STS | |
| SCHEMBL5303335 | 0.82 | KMT2A (0.43) | MMP13LMNANPSR1ALDH1A1KMT2A | |
| SCHEMBL5303340 | 0.82 | KMT2A (0.43) | MMP13LMNANPSR1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039782-A1 | TETRAZOLE DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2007-04-12 | — | — | WO | disclosed |