Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 6/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | FADS1 | O60427 | 2/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | F2R | P25116 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5324997 | 0.75 | GRM5 (0.59) | HSPD1HSPE1GRM5FADS1P2RX1 | |
| SCHEMBL5328612 | 0.72 | PARP1 (0.39) | ALOX15ALOX12MAPTTP53SMN1; SMN2 | |
| SCHEMBL24118913 | 0.69 | HSPD1 (0.75) | HSPD1HSPE1GRM5FADS1P2RX1 | |
| SCHEMBL24118861 | 0.67 | HSPD1 (1.00) | HSPD1HSPE1GRM5FADS1P2RX1 | |
| SCHEMBL28914079 | 0.67 | HSPD1 (0.56) | HSPD1HSPE1GRM5FADS1P2RX1 | |
| SCHEMBL21828994 | 0.67 | MAPT (0.61) | HSPD1HSPE1GRM5FADS1P2RX1 | |
| SCHEMBL12225785 | 0.66 | FADS1 (0.70) | FADS1P2RX1P2RX4P2RX7TP53 | |
| SCHEMBL25226774 | 0.66 | HSPD1 (0.65) | HSPD1HSPE1GRM5FADS1P2RX1 | |
| SCHEMBL330366 | 0.66 | P2RX1 (0.78) | HSPD1HSPE1FADS1P2RX1P2RX4 | |
| SCHEMBL15778718 | 0.65 | FADS1 (0.74) | FADS1P2RX1P2RX4P2RX7MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007028789-A1 | QUINAZOLINE DERIVATIVES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2007-03-15 | — | — | WO | disclosed |