Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.59 |
| ▸ | FADS1 | O60427 | 3/20 | 0.57 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.53 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.48 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15622414 | 0.77 | ALOX15 (0.45) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5330657 | 0.75 | HSPD1 (0.50) | GRM5FADS1P2RX1P2RX4P2RX7 | |
| SCHEMBL15778718 | 0.74 | FADS1 (0.74) | FADS1P2RX1P2RX4P2RX7NPC1 | |
| SCHEMBL2701738 | 0.73 | FADS1 (1.00) | FADS1P2RX1P2RX4P2RX7NPC1 | |
| SCHEMBL15778670 | 0.73 | FADS1 (0.68) | GRM5FADS1P2RX1P2RX4P2RX7 | |
| SCHEMBL16007625 | 0.72 | MEN1 (0.76) | FADS1P2RX1P2RX4P2RX7NPC1 | |
| SCHEMBL4718180 | 0.72 | NPC1 (0.55) | NPC1RAB9AGRM4HDAC6SMN1; SMN2 | |
| SCHEMBL472983 | 0.72 | FADS1 (0.78) | GRM5FADS1P2RX1P2RX4P2RX7 | |
| SCHEMBL12225785 | 0.72 | FADS1 (0.70) | FADS1P2RX1P2RX4P2RX7NPC1 | |
| SCHEMBL15778871 | 0.72 | FADS1 (0.70) | FADS1P2RX1P2RX4P2RX7NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007028789-A1 | QUINAZOLINE DERIVATIVES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2007-03-15 | — | — | WO | disclosed |