SCHEMBL5330904

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27412663	0.83	NPC1 (0.74)	MAPTNPC1RAB9AACHECHRNB2
	SCHEMBL13415305	0.82	ACHE (0.80)	MAPTNPC1RAB9AACHETP53
	SCHEMBL12653007	0.81	NPC1 (0.70)	MAPTNPC1RAB9ACHRNB2CHRNA5
	SCHEMBL6582079	0.80	MAPT (0.61)	MAPTNPC1RAB9ACHRNB2CHRNA5
	SCHEMBL31415475	0.78	ALDH1A1 (0.49)	MAPTNPC1RAB9ATP53LMNA
	SCHEMBL28987558	0.78	MAPT (0.43)	MAPTNPC1RAB9AACHECHRNB2
	SCHEMBL30481034	0.78	MAPT (0.43)	MAPTNPC1RAB9AACHECHRNB2
	SCHEMBL8825392	0.78	MAPT (0.58)	MAPTNPC1RAB9ACHRNB2CHRNA5
	SCHEMBL11715801	0.78	NPC1 (0.76)	MAPTNPC1RAB9ACHRNB2CHRNA5
	SCHEMBL16592426	0.78	NPC1 (0.76)	MAPTNPC1RAB9ACHRNB2CHRNA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.