Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31415253 | 0.82 | ALDH1A1 (0.43) | ALDH1A1TDP1TSHRGAAMAPT | |
| SCHEMBL5330904 | 0.78 | MAPT (0.61) | ALDH1A1MAPTNPC1RAB9AMEN1 | |
| SCHEMBL12653007 | 0.77 | NPC1 (0.70) | ALDH1A1TDP1GAAMAPTCYP3A4 | |
| SCHEMBL16481865 | 0.76 | RAB9A (0.46) | ALDH1A1TDP1TSHRGAAMAPT | |
| SCHEMBL4265596 | 0.73 | ALDH1A1 (0.49) | ALDH1A1TDP1TSHRMAPTCYP3A4 | |
| SCHEMBL11980663 | 0.73 | ALDH1A1 (0.49) | ALDH1A1TDP1TSHRMAPTCYP3A4 | |
| SCHEMBL19551446 | 0.73 | ALDH1A1 (0.50) | ALDH1A1TDP1GAAMAPTCYP3A4 | |
| SCHEMBL12909247 | 0.73 | ACHE (0.46) | TSHRGAAMAPTPIK3CDMTOR | |
| SCHEMBL31415554 | 0.73 | ACHE (0.59) | ALDH1A1TSHRGAAMAPTPIK3CD | |
| SCHEMBL6367373 | 0.73 | MAPT (0.59) | ALDH1A1TDP1GAAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054368-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | NICO THERAPEUTICS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |