Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27562870 | 0.80 | TUBB4A (0.41) | GAAALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL948160 | 0.80 | HPGD (0.56) | GAAALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL13396265 | 0.80 | HPGD (0.56) | GAAALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL7056333 | 0.80 | HPGD (0.56) | GAAALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL11292044 | 0.79 | ALDH1A1 (0.50) | GAAALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL4553590 | 0.78 | NPSR1 (0.68) | GAAALDH1A1RAB9ALMNAMEN1 | |
| SCHEMBL9815318 | 0.77 | LMNA (0.61) | ALDH1A1SMN1; SMN2HPGDRAB9ALMNA | |
| SCHEMBL4689551 | 0.77 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2HPGDRAB9ALMNA | |
| SCHEMBL4689548 | 0.77 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2HPGDRAB9ALMNA | |
| SCHEMBL24998749 | 0.75 | MLYCD (0.58) | GAAALDH1A1SMN1; SMN2HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007065010-A2 | ANTI-ANGIOGENESIS COMPOUNDS | HIF BIO, INC. (US) | 2007-06-07 | — | — | WO | disclosed |
| CN-1241188-A | Heterocyclylmethyl-substed pyrazol derivs. | BAYER AG (DE) | 2000-01-12 | — | — | CN | disclosed |
| EP-0934311-A2 | NEW HETEROCYCLYLMETHYL-SUBSTITUTED PYRAZOL DERIVATES | BAYER AG (DE) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998016507-A2 | NEW HETEROCYCLYLMETHYL-SUBSTITUTED PYRAZOL DERIVATES AND THEIR USE FOR TREATING CARDIOVASCULAR DISEASES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-04-23 | — | — | WO | disclosed |