Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | TPMT | P51580 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332098 | 0.82 | MEN1 (0.49) | CSNK2A1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL5339343 | 0.82 | ICAM1 (0.42) | MAPTHPGDMEN1KMT2ALMNA | |
| SCHEMBL5330795 | 0.81 | IRAK4 (0.47) | MAPTHPGDMEN1KMT2AMAPK1 | |
| SCHEMBL5337352 | 0.79 | GAA (0.43) | CSNK2A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL5313426 | 0.78 | PTGS1 (0.46) | CSNK2A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL5329633 | 0.76 | KMT2A (0.52) | MEN1KMT2ARAB9A | |
| SCHEMBL5333560 | 0.75 | MEN1 (0.55) | CSNK2A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL2935985 | 0.71 | PIM3 (0.58) | CSNK2A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL2217939 | 0.71 | CA12 (0.65) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL5331005 | 0.70 | CSNK2A1 (0.58) | CSNK2A1MAPTHPGDCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056215-A9 | N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF | CYTOVIA INC (US) | 2007-09-13 | — | — | WO | claimed |
| WO-2007056215-A2 | N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF | CYTOVIA, INC. (US) | 2007-05-18 | — | — | WO | claimed |