Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 5/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5339343 | 0.86 | ICAM1 (0.42) | KMT2AMEN1POLBHTTTP53 | |
| SCHEMBL5332098 | 0.86 | MEN1 (0.49) | KMT2AMEN1MAPK1TSHRNPC1 | |
| SCHEMBL5313426 | 0.82 | PTGS1 (0.46) | IRAK4KMT2AMEN1POLBMAPK1 | |
| SCHEMBL5331010 | 0.81 | CSNK2A1 (0.51) | KMT2AMEN1MAPK1HTTMAPT | |
| SCHEMBL5337352 | 0.80 | GAA (0.43) | KMT2AMEN1MAPK1TSHRNPC1 | |
| SCHEMBL5329633 | 0.80 | KMT2A (0.52) | KMT2AMEN1 | |
| SCHEMBL5333560 | 0.79 | MEN1 (0.55) | KMT2AMEN1MAPK1NPC1HTT | |
| SCHEMBL23565733 | 0.76 | KMT2A (0.61) | KMT2AMEN1POLBMAPK1TSHR | |
| SCHEMBL5335650 | 0.74 | EPAS1 (0.43) | KMT2AMEN1TSHRNPC1TP53 | |
| SCHEMBL5317673 | 0.73 | TSHR (0.42) | MAPK1TSHRHTTTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056215-A9 | N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF | CYTOVIA INC (US) | 2007-09-13 | — | — | WO | claimed |
| WO-2007056215-A2 | N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF | CYTOVIA, INC. (US) | 2007-05-18 | — | — | WO | claimed |