Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 4/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.41 |
| ▸ | CLK1 | P49759 | 3/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5335650 | 0.81 | EPAS1 (0.43) | KMT2AMEN1CLK1SRCRAB9A | |
| SCHEMBL5339343 | 0.81 | ICAM1 (0.42) | KMT2AMEN1 | |
| SCHEMBL5332098 | 0.81 | MEN1 (0.49) | KMT2AMEN1EGFR | |
| SCHEMBL5330795 | 0.80 | IRAK4 (0.47) | KMT2AMEN1 | |
| SCHEMBL5339543 | 0.79 | TNF (0.55) | KMT2AMEN1RAB9APDE10A | |
| SCHEMBL5313426 | 0.78 | PTGS1 (0.46) | KMT2AMEN1RAB9A | |
| SCHEMBL5333560 | 0.78 | MEN1 (0.55) | KMT2AMEN1ALOX5RAB9A | |
| SCHEMBL5340653 | 0.76 | EPAS1 (0.39) | KMT2AMEN1CLK1SRCRAB9A | |
| SCHEMBL5336441 | 0.76 | CSNK2A1 (0.39) | KMT2AMEN1SRCRAB9A | |
| SCHEMBL5331010 | 0.76 | CSNK2A1 (0.51) | KMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056215-A9 | N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF | CYTOVIA INC (US) | 2007-09-13 | — | — | WO | claimed |
| WO-2007056215-A2 | N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF | CYTOVIA, INC. (US) | 2007-05-18 | — | — | WO | claimed |