Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.45 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332098 | 0.90 | MEN1 (0.49) | MEN1KMT2ACSNK2A1GAANPC1 | |
| SCHEMBL5313426 | 0.83 | PTGS1 (0.46) | MEN1KMT2ACSNK2A1GAANPC1 | |
| SCHEMBL5335650 | 0.80 | EPAS1 (0.43) | MEN1KMT2ACSNK2A1NPC1RAB9A | |
| SCHEMBL5339343 | 0.80 | ICAM1 (0.42) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL5337352 | 0.79 | GAA (0.43) | MEN1KMT2ACSNK2A1GAANPC1 | |
| SCHEMBL5330795 | 0.79 | IRAK4 (0.47) | MEN1KMT2ANPC1MAPTKDM4E | |
| SCHEMBL5329633 | 0.78 | KMT2A (0.52) | MEN1KMT2ARAB9AALOX5 | |
| SCHEMBL5336441 | 0.75 | CSNK2A1 (0.39) | MEN1KMT2ACSNK2A1NPC1RAB9A | |
| SCHEMBL5340653 | 0.75 | EPAS1 (0.39) | MEN1KMT2ACSNK2A1NPC1RAB9A | |
| SCHEMBL5331010 | 0.75 | CSNK2A1 (0.51) | MEN1KMT2ACSNK2A1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056215-A9 | N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF | CYTOVIA INC (US) | 2007-09-13 | — | — | WO | disclosed |
| WO-2007056215-A2 | N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF | CYTOVIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |