Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 7/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5331609 | 0.81 | TSHR (0.43) | TSHRL3MBTL1LMNANPY5RKMT2A | |
| SCHEMBL5331537 | 0.80 | TSHR (0.46) | TSHRKLK7ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL5329549 | 0.78 | TDP1 (0.39) | KMT2A | |
| SCHEMBL5331113 | 0.78 | TSHR (0.43) | TSHRKLK7POLBSMN1; SMN2 | |
| SCHEMBL5324604 | 0.76 | TSHR (0.46) | TSHRKLK7ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL5331601 | 0.72 | FAAH (0.39) | LMNASMN1; SMN2 | |
| SCHEMBL5331540 | 0.71 | ADRB2 (0.42) | TSHRALDH1A1L3MBTL1MAPK1ADRB2 | |
| SCHEMBL5330077 | 0.71 | FOLH1 (0.40) | TSHRKLK7 | |
| SCHEMBL18848232 | 0.70 | TSHR (0.56) | TSHRKLK7ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL18848357 | 0.70 | TSHR (0.56) | TSHRKLK7ALDH1A1L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007146086-A1 | CREATINE PRODRUGS, COMPOSITIONS AND USES THEREOF | XENOPORT, INC. (US) | 2007-12-21 | — | — | WO | disclosed |