Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 10/20 | 0.44 |
| ▸ | HTR6 | P50406 | 9/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5333545 | 0.93 | HTR6 (0.41) | PTGDR2HTR6 | |
| SCHEMBL5407869 | 0.90 | PTGDR2 (0.54) | PTGDR2HTR6PTGDR | |
| SCHEMBL5326862 | 0.90 | HTR6 (0.49) | PTGDR2HTR6PTGDR | |
| SCHEMBL5326887 | 0.90 | HTR6 (0.40) | PTGDR2HTR6PTGDRAKR1B1 | |
| SCHEMBL5332248 | 0.88 | HTR6 (0.44) | PTGDR2HTR6PTGDR | |
| SCHEMBL5424103 | 0.88 | DDR1 (0.35) | PTGDR2HTR6PTGDR | |
| SCHEMBL5420518 | 0.86 | PTGDR2 (0.45) | PTGDR2HTR6PTGDR | |
| SCHEMBL5328966 | 0.86 | PTGDR2 (0.55) | PTGDR2HTR6PTGDR | |
| SCHEMBL5330910 | 0.85 | HTR6 (0.51) | PTGDR2HTR6PTGDR | |
| SCHEMBL5332687 | 0.84 | HTR6 (0.56) | PTGDR2HTR6PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |