Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.38 |
| ▸ | CNR1 | P21554 | 4/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5327891 | 0.88 | MAPT (0.43) | NPC1RAB9AMAPTLMNAHSD11B1 | |
| SCHEMBL5332143 | 0.84 | GALR3 (0.34) | MAPTGALR3LMNASTAT3SMN1; SMN2 | |
| SCHEMBL5334515 | 0.77 | CHRNB2 (0.38) | CHRNB2CHRNA4BRD4MAPTLMNA | |
| SCHEMBL5335652 | 0.77 | KMT2A (0.40) | CHRNB2CHRNA4RAB9ABRD4MAPT | |
| SCHEMBL23982537 | 0.68 | CHRNB2 (0.46) | CHRNB2CHRNA4NPC1RAB9AREN | |
| SCHEMBL5331359 | 0.68 | NPC1 (0.38) | CNR2CNR1CHRNB2CHRNA4NPC1 | |
| SCHEMBL5802048 | 0.68 | CNR2 (0.35) | CNR2CNR1CHRNB2CHRNA4NPC1 | |
| SCHEMBL5306222 | 0.65 | NOTUM (0.53) | CHRNB2CHRNA4NPC1RAB9AREN | |
| SCHEMBL22407028 | 0.65 | NPC1 (0.43) | NPC1RAB9AMAPTSMN1; SMN2HSD11B1 | |
| SCHEMBL15081822 | 0.64 | MEN1 (0.46) | CNR2CNR1NPC1RAB9ABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007034445-A2 | NOVEL PIPERAZINE DERIVATIVES AS RENIN INHIBITORS FOR CARDIOVASCULAR EVENTS AND RENAL INSUFFICIENCY | ACTELION PHARMACEUTICALS LTD (CH) | 2007-03-29 | — | — | WO | disclosed |