Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.43 |
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24168447 | 0.82 | POLB (0.40) | NPC1RAB9AL3MBTL1TSHRPOLB | |
| SCHEMBL30334696 | 0.82 | POLB (0.40) | NPC1RAB9AL3MBTL1TSHRPOLB | |
| SCHEMBL11965513 | 0.78 | NPC1 (0.44) | NPC1RAB9AL3MBTL1TP53HPGD | |
| SCHEMBL22406988 | 0.78 | L3MBTL1 (0.34) | NPC1RAB9AL3MBTL1POLBMAPT | |
| SCHEMBL30494642 | 0.78 | L3MBTL1 (0.34) | NPC1RAB9AL3MBTL1POLBMAPT | |
| SCHEMBL28977122 | 0.76 | RAB9A (0.51) | NPC1RAB9AL3MBTL1TP53POLB | |
| SCHEMBL30702173 | 0.73 | NPC1 (0.36) | NPC1RAB9AL3MBTL1HPGDPOLB | |
| SCHEMBL24168949 | 0.73 | POLB (0.40) | NPC1RAB9AL3MBTL1HPGDTSHR | |
| SCHEMBL20360230 | 0.73 | NPC1 (0.36) | NPC1RAB9AL3MBTL1HPGDPOLB | |
| SCHEMBL30334691 | 0.72 | RARA (0.35) | NPC1RAB9AL3MBTL1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111683930-B | Novel isoxazole compound or salt thereof | 日本欧爱特农业科技株式会社 | 2023-06-27 | — | — | CN | disclosed |
| EP-3717461-B1 | A NOVEL ISOXAZOLE COMPOUND OR A SALT THEREOF | OAT AGRIO CO LTD (JP) | 2022-06-15 | — | — | EP | disclosed |
| US-11116218-B2 | Isoxazole compound or a salt thereof | OAT AGRIO CO., LTD. (JP) | 2021-09-14 | — | — | US | disclosed |
| EP-3717461-A1 | A NOVEL ISOXAZOLE COMPOUND OR A SALT THEREOF | OAT Agrio Co., Ltd. (JP) | 2020-10-07 | — | — | EP | disclosed |
| CN-111683930-A | Novel isoxazole compound or salt thereof | 日本欧爱特农业科技株式会社 | 2020-09-18 | — | — | CN | disclosed |
| US-20200288717-A1 | A NOVEL ISOXAZOLE COMPOUND OR A SALT THEREOF | OAT & IIL INDIA LABORATORIES PRIVATE LIMITED (IN) | 2020-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11116218-B2 | Isoxazole compound or a salt thereof | HCN1, HAX1, HCN4 | NPC1 492/4885RAB9A 1471/4885L3MBTL1 951/4885 |
| US-20200288717-A1 | A NOVEL ISOXAZOLE COMPOUND OR A SALT THEREOF | HAX1, HCN1, HCN4 | NPC1 730/4885RAB9A 1308/4885L3MBTL1 746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.