Sugi Predict

Sugi Predict / Compounds / SCHEMBL533179

SCHEMBL533179

SCHEMBL533179

Nc1ncnc2c1c(I)nn2C1CC(O)C(CO)O1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ATG7 O95352 11/20 0.71
▸ ADK P55263 7/20 0.65
▸ DYRK3 O43781 2/20 0.65
▸ CDK1 P06493 2/20 0.65
▸ ROS1 P08922 2/20 0.65
▸ RPS6KB1 P23443 2/20 0.65
▸ CDK2 P24941 2/20 0.65
▸ CSNK1A1 P48729 2/20 0.65
▸ CSNK1D P48730 2/20 0.65
▸ CLK2 P49760 2/20 0.65
▸ IRAK1 P51617 2/20 0.65
▸ CDK5 Q00535 2/20 0.65
▸ DYRK1A Q13627 2/20 0.65
▸ NTRK3 Q16288 2/20 0.65
▸ SLK Q9H2G2 2/20 0.65
▸ CLK4 Q9HAZ1 2/20 0.65
▸ DOT1L Q8TEK3 1/20 0.65
▸ DCLK1 O15075 1/20 0.65
▸ DAPK3 O43293 1/20 0.65
▸ FLT3 P36888 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13337873 1.00 ATG7 (0.71) ATG7ADKDYRK3CDK1ROS1
SCHEMBL2909424 1.00 ATG7 (0.71) ATG7ADKDYRK3CDK1ROS1
SCHEMBL20141774 1.00 ATG7 (0.71) ATG7ADKDYRK3CDK1ROS1
SCHEMBL20142486 1.00 ATG7 (0.71) ATG7ADKDYRK3CDK1ROS1
SCHEMBL14038325 0.87 ATG7 (0.57) ATG7
SCHEMBL2908818 0.86 ATG7 (0.55) ATG7ADKDYRK3CDK1ROS1
SCHEMBL12762314 0.85 ATG7 (0.54) ATG7
SCHEMBL20142123 0.84 ATG7 (0.74) ATG7
SCHEMBL20141551 0.84 ATG7 (0.74) ATG7
SCHEMBL22758711 0.84 ATG7 (1.00) ATG7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1430147-B1 FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS EPOCH BIOSCIENCES INC (US) 2013-05-22 — — EP disclosed
EP-1235938-B1 FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS EPOCH BIOSCIENCES INC (US) 2012-02-08 — — EP disclosed
US-7897736-B2 Fluorescent quenching detecting reagents and methods ELITECH HOLDING B.V. (NL) 2011-03-01 — — US disclosed
US-7897736-B2 Fluorescent quenching detecting reagents and methods ELITECH HOLDING B.V. (NL) 2011-03-01 — — US disclosed
US-7897736-B2 Fluorescent quenching detecting reagents and methods ELITECH HOLDING B.V. (NL) 2011-03-01 — — US disclosed
US-20100174058-A1 FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS ELITECHGROUP, INC. 2010-07-08 — — US disclosed
US-20100174058-A1 FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS ELITECHGROUP, INC. 2010-07-08 — — US disclosed
US-20100174058-A1 FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS ELITECHGROUP, INC. 2010-07-08 — — US disclosed
US-7662942-B2 Oligonucleotide probes containing two labels useful in hybridization assays Elitech Holdings, B.V. (NL) 2010-02-16 — — US disclosed
US-7662942-B2 Oligonucleotide probes containing two labels useful in hybridization assays Elitech Holdings, B.V. (NL) 2010-02-16 — — US disclosed
US-6727356-B1 AS PROBES SUCH AS FOR FLUORESCENCE RESONANCE ENERGY TRANSFER; QUENCHER INCLUDES A 4-(PHENYLDIAZENYL)PHENYLAMINE STRUCTURE; IMPROVED SIGNAL TO NOISE RATIO AND HYBRIDIZATION EPOCH PHARMACEUTICALS, INC. 2004-04-27 — — US disclosed
US-6699975-B2 OLIGONUCLEOTIDE FOR USE AS TOOL IN THE DETECTION OF PREFERENTIAL COMPOUNDS IN SOLUTION EPOCH BIOSCIENCES, INC. 2004-03-02 — — US disclosed
US-6653473-B2 Nucleotide sequences for use as diagnostic tool in genetic analysis EPOCH BIOSCIENCES, INC. 2003-11-25 — — US disclosed
US-20030096254-A1 Enhancing resonance ability of oligonuclotide probes for use in hybridization assays; gene expression EPOCH BIOSCIENCES, INC. (US) 2003-05-22 — — US disclosed
US-20030008304-A1 Fluorescent quenching detection reagents and methods EPOCH BIOSCIENCES, INC. (US) 2003-01-09 — — US disclosed
WO-2002099141-A1 FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS EPOCH BIOSCIENCES, INC. (US) 2002-12-12 — — WO disclosed
US-20020155484-A1 Fluorescent quenching detection reagents and methods EPOCH PHARMACEUTICALS, INC. (US) 2002-10-24 — — US disclosed
EP-1235938-A2 FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS Epoch Biosciences, Inc. (US) 2002-09-04 — — EP disclosed
US-20020034754-A1 Fluorescent quenching detection reagents and methods ELITECHGROUP, INC. 2002-03-21 — — US disclosed
WO-2001042505-A2 FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS EPOCH BIOSCIENCES, INC. (US) 2001-06-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030008304-A1 Fluorescent quenching detection reagents and methods DDX5, DDX21, DCLRE1B ATG7 4280/4885ADK 3936/4885DYRK3 3393/4885
US-20020034754-A1 Fluorescent quenching detection reagents and methods DDX5, DDX21, DCLRE1B ATG7 4280/4885ADK 3936/4885DYRK3 3393/4885
US-20100174058-A1 FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS DDX5, DDX21, DCLRE1B ATG7 4097/4885ADK 3969/4885DYRK3 3614/4885
US-20020155484-A1 Fluorescent quenching detection reagents and methods IPO4, PTBP3, DDX5 ATG7 4871/4885ADK 4530/4885DYRK3 620/4885
US-20030096254-A1 Enhancing resonance ability of oligonuclotide probes for use in hybridization assays; gene expression DCLRE1B, SNRPE, ZFR ATG7 4784/4885ADK 4693/4885DYRK3 4102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.