Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 2/20 | 0.38 |
| ▸ | MELK | Q14680 | 2/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | SCN8A | Q9UQD0 | 13/20 | 0.36 |
| ▸ | SCN1A | P35498 | 12/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14531378 | 0.81 | MELK (0.39) | MAP4K4MELKGRM2SCN8ASCN1A | |
| SCHEMBL5336063 | 0.75 | GRM2 (0.37) | MAP4K4MELKGRM2SCN8ASCN1A | |
| SCHEMBL5315529 | 0.70 | DYRK2 (0.40) | — | |
| SCHEMBL5316079 | 0.68 | CDK4 (0.40) | — | |
| SCHEMBL14531377 | 0.67 | DYRK2 (0.40) | — | |
| SCHEMBL5313455 | 0.67 | DYRK2 (0.47) | — | |
| SCHEMBL5312799 | 0.67 | KDR (0.41) | — | |
| SCHEMBL5314116 | 0.67 | DYRK2 (0.39) | — | |
| SCHEMBL2883883 | 0.65 | HRH3 (0.52) | MAP4K4MELKGRM2 | |
| SCHEMBL5312932 | 0.65 | KDR (0.42) | MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |