Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.37 |
| ▸ | SCN1A | P35498 | 6/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 6/20 | 0.36 |
| ▸ | CDK4 | P11802 | 3/20 | 0.36 |
| ▸ | CCND1 | P24385 | 2/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.36 |
| ▸ | CDK9 | P50750 | 2/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.35 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | MELK | Q14680 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCND3 | P30281 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311867 | 0.85 | MERTK (0.45) | CDK4TNIKCDK6MERTKCCNA2 | |
| SCHEMBL5314922 | 0.85 | PDE1B (0.35) | GRM2CDK4CCND1CCNT1CDK9 | |
| SCHEMBL5313507 | 0.85 | DYRK2 (0.45) | CDK4CCND1CDK6MERTKKDR | |
| SCHEMBL5315261 | 0.85 | BDKRB1 (0.37) | CDK4CCND1CCNT1CDK9CDK6 | |
| SCHEMBL14531378 | 0.78 | MELK (0.39) | GRM2MAP4K4SCN1ASCN8ACDK4 | |
| SCHEMBL5333911 | 0.76 | MERTK (0.38) | GRM2MAP4K4CCNT1CDK9FLT3 | |
| SCHEMBL5311883 | 0.76 | TNIK (0.45) | GRM2CDK4TNIKCDK6MERTK | |
| SCHEMBL5315552 | 0.75 | BDKRB1 (0.40) | GRM2CDK4CCND1CDK6CNR2 | |
| SCHEMBL5331801 | 0.75 | MAP4K4 (0.38) | GRM2MAP4K4SCN1ASCN8AMELK | |
| SCHEMBL5334782 | 0.74 | MERTK (0.43) | MERTKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | claimed |