Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1759579 | 0.85 | ADRA1A (0.64) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2096168 | 0.84 | CA12 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3924349 | 0.84 | CA12 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11709428 | 0.82 | ADRA2A (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28119250 | 0.82 | CA12 (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31439778 | 0.82 | ADRA2A (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8785084 | 0.79 | CA12 (0.60) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2975604 | 0.79 | ADRA1A (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28802621 | 0.79 | CA12 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29684720 | 0.79 | ADRA1A (0.57) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4075340-A | ANTIINFLAMMATORY, ANTIARRYTHMIC, ANTICOAGULANTS | PARCOR (FR) | 1978-02-21 | — | — | US | claimed |
| US-7182934-B2 | Ultrasonic contrast agents; aqueous suspension | GE HEALTHCARE AS (NO) | 2007-02-27 | — | — | US | disclosed |
| EP-0971747-B1 | CONTRAST AGENTS | AMERSHAM HEALTH AS (NO) | 2005-12-28 | — | — | EP | disclosed |
| US-20050201930-A1 | Contrast agents | GE HEALTHCARE AS (NO) | 2005-09-15 | — | — | US | disclosed |
| US-6921525-B2 | Contrast agents | AMERSHAM HEALTH AS (NO) | 2005-07-26 | — | — | US | disclosed |
| US-6524552-B2 | Imaging cardiovascular disorders | GE HEALTHCARE AS (NO) | 2003-02-25 | — | — | US | disclosed |
| US-6264914-B1 | CONTAINING IMIDAZOLE RING | NYCOMED IMAGING AS (NO) | 2001-07-24 | — | — | US | disclosed |
| EP-0971747-A2 | CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998018496-A2 | CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 1998-05-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050201930-A1 | Contrast agents | AGTR1, AGTR2, VIPR1 | CA12 966/4885CA1 454/4885CA2 360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.