Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 9/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 7/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 7/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL5330246 | 0.93 | HTR1A (0.46) | HTR1ADRD2HTR2AADRA1AADRA1B | |
| SCHEMBL5330473 | 0.92 | ADRA1A (0.41) | HTR1ADRD2HTR2AADRA1AADRA1B | |
| SCHEMBL4519413 | 0.91 | DRD2 (0.48) | HTR1ADRD2HTR2AADRA1AADRA1B | |
| SCHEMBL14541002 | 0.91 | DRD2 (0.48) | HTR1ADRD2HTR2AADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL4520297 | 0.90 | DRD2 (0.48) | HTR1ADRD2HTR2AADRA1AADRA1B | |
| Phosphoric Acid SCHEMBL5330466 | 0.89 | HTR1A (0.43) | HTR1ADRD2HTR2AADRA1AADRA1B | |
| SCHEMBL5326464 | 0.88 | HTR1A (0.50) | HTR1ADRD2HTR2AADRA1AADRA1B | |
| SCHEMBL5330072 | 0.88 | HTR1A (0.40) | HTR1ADRD2HTR2AADRA1AADRA1B | |
| SCHEMBL5330901 | 0.88 | ADRA1A (0.41) | DRD2ADRA1AADRA1BADRA1D | |
| SCHEMBL5327011 | 0.88 | ADRA1D (0.42) | HTR1ADRD2ADRA1AADRA1BADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007010504-A2 | ACID ADDITION SALTS OF ISOINDOLES ACTING AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-01-25 | — | — | WO | disclosed |