Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.67 |
| ▸ | HRH1 | P35367 | 4/20 | 0.67 |
| ▸ | HRH2 | P25021 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | LTA4H | P09960 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9097701 | 0.94 | LTA4H (0.66) | HRH3HRH1HRH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL5455464 | 0.92 | LTA4H (0.69) | HRH3HRH1HRH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL5752269 | 0.89 | LTA4H (0.64) | HRH3HRH1HRH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL22266155 | 0.88 | LTA4H (0.62) | HRH3KCNH2LTA4H | |
| SCHEMBL22266165 | 0.87 | LTA4H (0.58) | HRH3HRH1HRH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9122265 | 0.85 | LTA4H (0.77) | ALDH1A1SMN1; SMN2KDM4ELTA4HMEN1 | |
| SCHEMBL211606 | 0.85 | LTA4H (0.77) | ALDH1A1SMN1; SMN2KDM4ELTA4HMEN1 | |
| SCHEMBL492205 | 0.85 | HRH3 (0.84) | HRH3HRH1HRH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL1714272 | 0.84 | HRH3 (0.92) | HRH3HRH1HRH2 | |
| SCHEMBL2823877 | 0.84 | HRH3 (0.87) | HRH3HRH1HRH2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117903096-A | Cinnamoyl-substituted unsaturated nitrogen-containing heterocycle-containing oxygen-containing compound, composition, preparation method and application | 贵州大学 | 2024-04-19 | — | — | CN | disclosed |
| US-20070213359-A1 | BICYCLIC-NITROGEN COMPOUNDS AS MODULATORS OF GHRELIN RECEPTOR AND USES THEREOF | ACADIA PHARMACEUTICALS INC. (US) | 2007-09-13 | — | — | US | disclosed |
| US-20070213359-A1 | BICYCLIC-NITROGEN COMPOUNDS AS MODULATORS OF GHRELIN RECEPTOR AND USES THEREOF | ACADIA PHARMACEUTICALS INC. (US) | 2007-09-13 | — | — | US | disclosed |
| US-20070213359-A1 | BICYCLIC-NITROGEN COMPOUNDS AS MODULATORS OF GHRELIN RECEPTOR AND USES THEREOF | ACADIA PHARMACEUTICALS INC. (US) | 2007-09-13 | — | — | US | disclosed |
| WO-2007079239-A2 | BICYCLIC NITROGEN COMPOUNDS AS MODULATORS OF GHRELIN RECEPTOR AND USES THEREOF | ACADIA PHARMACEUTICALS INC. (US) | 2007-07-12 | — | — | WO | disclosed |
| WO-2007079239-A2 | BICYCLIC NITROGEN COMPOUNDS AS MODULATORS OF GHRELIN RECEPTOR AND USES THEREOF | ACADIA PHARMACEUTICALS INC. (US) | 2007-07-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213359-A1 | BICYCLIC-NITROGEN COMPOUNDS AS MODULATORS OF GHRELIN RECEPTOR AND USES THEREOF | GIPR, GHSR, GHRHR | HRH3 527/4885HRH1 502/4885HRH2 418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.