Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | DRD4 | P21917 | 3/20 | 0.52 |
| ▸ | DRD3 | P35462 | 3/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5330012 | 0.89 | HTR2A (0.49) | DRD2DRD4DRD3CHRNA7HTR6 | |
| SCHEMBL5334148 | 0.87 | POLB (0.44) | DRD2DRD4DRD3CHRNA7HTR6 | |
| SCHEMBL5332260 | 0.87 | POLB (0.44) | DRD2DRD4DRD3CHRNA7HTR6 | |
| SCHEMBL5331577 | 0.87 | MPO (0.48) | DRD2DRD4DRD3CHRNA7HTR6 | |
| SCHEMBL5329102 | 0.85 | KDM4E (0.46) | DRD2DRD3HTR6POLBKMT2A | |
| SCHEMBL5334658 | 0.82 | DRD2 (0.46) | DRD2DRD4DRD3CHRNA7POLB | |
| SCHEMBL5333420 | 0.77 | MPO (0.47) | DRD2DRD4DRD3POLBKDM4E | |
| SCHEMBL5332148 | 0.77 | KMT2A (0.44) | POLBMAPTKMT2AGAAKDM4E | |
| SCHEMBL946707 | 0.77 | POLB (0.67) | DRD2DRD4DRD3CHRNA7HTR6 | |
| SCHEMBL5335447 | 0.76 | DRD2 (0.50) | DRD2DRD4DRD3CHRNA7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | claimed |
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | disclosed |