Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5135169 | 0.74 | PARP1 (0.39) | OPRL1 | |
| SCHEMBL5135172 | 0.74 | OPRM1 (0.37) | OPRL1 | |
| SCHEMBL5134855 | 0.73 | OPRL1 (0.34) | OPRL1 | |
| SCHEMBL5332667 | 0.64 | — | — | |
| SCHEMBL5332673 | 0.64 | CNR1 (0.33) | OPRL1 | |
| SCHEMBL5190879 | 0.63 | IRAK4 (0.36) | — | |
| SCHEMBL3614452 | 0.61 | PARP10 (0.35) | — | |
| SCHEMBL5134806 | 0.61 | PARP2 (0.39) | — | |
| SCHEMBL5134530 | 0.58 | PARP1 (0.33) | OPRL1 | |
| SCHEMBL5134854 | 0.58 | CNR1 (0.37) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007053400-A2 | PIPERIDINE GLYCINE TRANSPORTER INHIBITORS | MERCK & CO., INC. (US) | 2007-05-10 | — | — | WO | disclosed |