Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5331944 | 0.84 | KMT2A (0.68) | SMN1; SMN2ALDH1A1RECQLTDP1KDM4E | |
| SCHEMBL5335319 | 0.82 | KMT2A (0.60) | SMN1; SMN2ALDH1A1RECQLTDP1KDM4E | |
| SCHEMBL5329001 | 0.82 | KMT2A (0.60) | SMN1; SMN2ALDH1A1RECQLTDP1KDM4E | |
| SCHEMBL5422195 | 0.77 | GAA (0.62) | ALDH1A1RECQLKDM4EGAAKMT2A | |
| SCHEMBL5329313 | 0.77 | HTT (0.62) | SMN1; SMN2ALDH1A1TDP1KDM4EPOLB | |
| SCHEMBL5329766 | 0.76 | GAA (0.64) | ALDH1A1RECQLKDM4EGAAKMT2A | |
| SCHEMBL5329305 | 0.74 | LMNA (0.54) | SMN1; SMN2ALDH1A1RECQLKDM4EGAA | |
| SCHEMBL5422247 | 0.74 | HSD17B10 (0.67) | SMN1; SMN2ALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL11920013 | 0.73 | ALDH1A1 (1.00) | SMN1; SMN2ALDH1A1RECQLTDP1KDM4E | |
| SCHEMBL8289705 | 0.72 | ALDH1A1 (0.84) | SMN1; SMN2ALDH1A1RECQLTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |