Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332719 | 0.84 | SMN1; SMN2 (0.67) | KMT2AALDH1A1GAACYP3A4CYP2C9 | |
| SCHEMBL5333893 | 0.77 | GAA (0.58) | KMT2AALDH1A1GAACYP3A4SMN1; SMN2 | |
| SCHEMBL5423806 | 0.77 | ALDH1A1 (0.64) | KMT2AALDH1A1GAASMN1; SMN2L3MBTL1 | |
| SCHEMBL5334239 | 0.76 | GAA (0.60) | KMT2AALDH1A1GAACYP3A4SMN1; SMN2 | |
| SCHEMBL5335319 | 0.75 | KMT2A (0.60) | KMT2AALDH1A1GAASMN1; SMN2L3MBTL1 | |
| SCHEMBL5329001 | 0.75 | KMT2A (0.60) | KMT2AALDH1A1GAASMN1; SMN2L3MBTL1 | |
| SCHEMBL5411483 | 0.75 | ALDH1A1 (0.61) | KMT2AALDH1A1GAASMN1; SMN2L3MBTL1 | |
| SCHEMBL5331366 | 0.74 | SMN1; SMN2 (0.70) | KMT2AALDH1A1GAASMN1; SMN2TSHR | |
| SCHEMBL5333083 | 0.70 | MAPT (0.68) | KMT2AALDH1A1CYP3A4CYP2C19L3MBTL1 | |
| SCHEMBL4206495 | 0.69 | L3MBTL1 (0.82) | KMT2AALDH1A1GAASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |