Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | RECQL | P46063 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5329001 | 1.00 | KMT2A (0.60) | KMT2AALDH1A1HSD17B10MAPTLMNA | |
| SCHEMBL14542415 | 0.83 | KMT2A (0.71) | KMT2AALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL14542394 | 0.83 | KMT2A (0.66) | KMT2AALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL5328923 | 0.82 | KMT2A (0.72) | KMT2AALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL5328915 | 0.82 | KMT2A (0.72) | KMT2AALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL5332719 | 0.82 | SMN1; SMN2 (0.67) | KMT2AALDH1A1HSD17B10SMN1; SMN2TDP1 | |
| SCHEMBL14542468 | 0.81 | ALDH1A1 (0.61) | KMT2AALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL5331944 | 0.75 | KMT2A (0.68) | KMT2AALDH1A1HSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL5331047 | 0.75 | KMT2A (0.62) | KMT2AALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL5330488 | 0.75 | KMT2A (0.62) | KMT2AALDH1A1MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | claimed |